Moisturizing agent

Abstract

Disclosed is a moisturizing agent comprising a copolymer represented by formula (1). [In formula (1), A represents a substituent containing an oligosaccharide composed of 2 to 6 monosaccharide molecules bound to each other; B represents a group represented by formula (2); m and n represent numbers which meet the following equation m:n=9:1 to 1:9; and Z represents a hydrogen group, a methyl group or an ethyl group.] [In formula (2), X represents a saturated or unsaturated monocyclic or dicyclic ring having 5 to 10 ring-constituting members, or a molecule containing a nitrogen or an oxygen, provided that the ring may contain 1 to 3 atoms independently selected from the group consisting of a nitrogen, a sulfur and an oxygen; n represents a number of 0 or 1; Y represents —NHCO—, —CONH—, —NHCONH—, —NH—, —CO, or an alkyl group having 0 or more carbon atoms; and R represents a linear or branched alkyl, alkenyl or alkynyl having 1 to 20 carbon atoms which, if required, may be substituted by one or two hydroxy, mercapto, amino, cyano, heterocyclyl, heterocyclyloxy, phenyl, benzyl, heteroaryl, phenoxy, benzyloxy or heteroaryloxy groups.]

1 . A moisturizer comprising a copolymer of formula (1): 
       
         
           
           
               
               
           
         
         [wherein 
         A is a substituent containing an oligosaccharide in which 2 to 6 monosaccharide molecules are bound to each other; 
         B is a group of formula (2): 
       
       
         
           
           
               
               
           
         
         (wherein X represents a 5- to 10-membered, saturated or unsaturated, monocyclic or dicyclic ring, or nitrogen- or oxygen-containing molecule, wherein the ring may contain 1 to 3 atom(s) selected from the group consisting of nitrogen, sulfur and oxygen; n is 0 or 1; Y is —NHCO—, —CONH—, —NHCONH—, —NH— or —CO—, or an alkyl group of 0 or more carbon(s); R is a linear or branched alkyl, alkenyl or alkynyl of 1 to 20 carbon(s), which may optionally be substituted with one or two hydroxy, mercapto, amino, cyano, heterocyclyl, heterocyclyloxy, phenyl, benzyl, heteroaryl, phenoxy, benzyloxy or heteroaryloxy); 
         m:n=9:1 to 1:9; 
         Z is a hydrogen group, methyl group or ethyl group]. 
       
     
     
         2 . A moisturizer comprising one or more copolymer(s) selected from the group consisting of:
 a copolymer of formula (3):   
       
         
           
           
               
               
           
         
         [wherein 
         m 1 :n 1  is 9:1 to 1:9; 
         x is an integer of 0 to 3; 
         Y is a single bond, —NHCO—, —NHCONH—, —CONH—, —OCONH—, —NHCOO—, —OCO—, —COO—, —CO— or —NH—; 
         R 1  is a saturated or unsaturated, monocyclic or dicyclic ring of 5 to 10 carbon(s), or a 5- or 6-membered heterocyclic ring containing O, S or N (wherein the monocyclic or dicyclic ring, or the heterocyclic ring may be unsubstituted or substituted with one or more group(s) selected from the group consisting of halogen, hydroxy, amino, thiol, cyano, cyclopentyl, cyclohexyl, phenyl and acetyl), or alkyl of 1 to 20 carbon(s) (wherein the alkyl may be interrupted with O, S or NH, and may be substituted with one or more group(s) selected from the group consisting of halogen, hydroxy, amino, thiol, cyano, cyclopentyl, cyclohexyl, phenyl and acetyl)], 
         a copolymer of formula (4): 
       
       
         
           
           
               
               
           
         
         (wherein m 2 :n 2 =9:1 to 1:9; R 1  is as defined for formula (3)); and 
         a copolymer of formula (5): 
       
       
         
           
           
               
               
           
         
         (wherein m 3 :n 3 =9:1 to 1:9). 
       
     
     
         3 . The moisturizer according to  claim 2 , wherein Y is NHCO— or —CONH—, and R 1  is alkyl of 1 to 20 carbon(s) (wherein the alkyl is substituted with halogen, hydroxy or cyclohexyl). 
     
     
         4 . The moisturizer according to any one of  claims 1  to  3 , wherein the content of the copolymer is 0.0001 to 5% by weight. 
     
     
         5 . A cosmetic comprising the moisturizer according to any one of  claims 1  to  3 , and a polysaccharide and/or a protein. 
     
     
         6 . The cosmetic according to  claim 5 , wherein the polysaccharide is chondroitin. 
     
     
         7 . The cosmetic according to  claim 5 , wherein the polysaccharide is hyaluronic acid. 
     
     
         8 . The cosmetic according to  claim 5 , wherein the protein is collagen or low-molecular-weight collagen.