Use of (R)-Penciclovir Triphosphate for the Manufacture of a Medicament for the Treatment of Viral Diseases

Abstract

A method of treatment of: i) HIV-1 infections in mammals, including humans; or ii) HBV infections in mammals, including humans; which method comprises the administration to the human in need of such treatment, an effective amount of the (R)-enantiomer of the triphosphate of a compound of formula (A) or a pharmaceutically acceptable salt thereof; and compounds for use in the method.

1 . A method of treatment of:
 i) HIV-1 infections in mammals, including humans; or   ii) HBV infections in mammals, including humans;   
       which method comprises the administration to the human in need of such treatment, an effective amount of the (R)-enantiomer of the triphosphate of a compound of formula (A): 
       
         
           
           
               
               
           
         
       
       ((R)-PCV-TP), or a pharmaceutically acceptable salt thereof. 
     
     
         2 . (canceled) 
     
     
         3 . (canceled) 
     
     
         4 . A method, composition, or use according to  claim 1  wherein the (R)-PCV-TP is in the form of a bioprecursor which is a derivative of (R)-PCV-MP which liberates intracellularly (R)-PCV-MP which is in turn converted to (R)-PCV-TP. 
     
     
         5 . (canceled) 
     
     
         6 . (canceled) 
     
     
         7 . (canceled)