Process for the preparation of active principles on thermal water and compositions comprising them

Abstract

The invention relates to a process for the preparation of a cosmetic or dermatological active principle, comprising the culturing of at least one nonphoto-synthetic and nonfruiting filamentous bacterium on a medium comprising at least one nonsulphurous mineral and/or thermal water. It also relates to a cosmetic or dermatological composition comprising at least one bacterium of the genus Vitreoscilla or one of its extracts.

1 . A process for preparing a cosmetic or dermatological active principle, comprising:
 culturing at least one nonphotosynthetic and nonfruiting filamentous bacterium on a medium comprising at least one nonsulphurous mineral and/or thermal water.   
     
     
         2 . The process according to  claim 1 , wherein a genus of the at least one bacterium is the genus  Vitreoscilla.    
     
     
         3 . The process according to  claim 2 , wherein a specie of the at least one bacterium is the specie,  Vitreoscilla filiformis.    
     
     
         4 . The process according to  claim 3 , wherein the bacterium is the strain deposited at the ATCC under the reference ATCC15551. 
     
     
         5 . The process according to  claim 1 , wherein a total mineral content of the thermal and/or mineral water is greater than or equal to 400 mg/l. 
     
     
         6 . The process according to  claim 1 , wherein the bacterium is cultured on a medium comprising a thermal water. 
     
     
         7 . The process according to  claim 1 , wherein a concentration of calcium ions in the thermal or mineral water is greater than or equal to 100 mg/l. 
     
     
         8 . The process according to  claim 1 , wherein a concentration of hydrogen-carbonates in the thermal or mineral water is greater than or equal to 300 mg/l. 
     
     
         9 . The process according to  claim 1 , wherein the bacterium is cultured on a medium comprising at least one thermal water selected from a group of waters consisting of water from Vittel, water from the Vichy basin, water from Uriage, water from La Roche-Posay, water from La Bourboule, water from Les Fumades, water from Enghien-les-Bains and water from Eaux-Bonnes. 
     
     
         10 . The process according to  claim 9 , wherein the thermal water is water from La Roche-Posay, water from Vittel or a mixture thereof. 
     
     
         11 . The process according to  claim 1 , further comprising:
 fermenting the cultured bacterium in the medium; and   separating the fermented cultured bacterium from the fermented culture medium to recover a mass of the bacteria;   wherein   the medium further comprises a monosaccharide, and   an order of the at least one bacterium is  Beggiatoales.      
     
     
         12 . The process according to  claim 11 , further comprising: stabilizing the mass of the bacteria which is recovered on conclusion of the fermentation stage. 
     
     
         13 . The process according to  claim 1 ,
 wherein   the culture medium comprises a mixture of (i) osmotically treated or distilled water and of (ii) thermal water, and   a ratio (i)/(ii) is between 1 and 100.   
     
     
         14 . The process according to  claim 1 , wherein the bacterium is of a genus  Vitreoscilla.    
     
     
         15 . A cosmetic or dermatological composition, comprising in a physiologically acceptable medium, at least one bacterium of the genus  Vitreoscilla  obtained by the process according to  claim 14 , or an extract of the at least one bacterium of the genus  Vitreoscilla.