Reconstitution and applicator system for wound sealant product

Abstract

A system for mixing or reconstituting agents including engageable syringe barrels, one of which having a male engagement region and the other a female engagement region. Each of the male and female engagement regions is provided with a screen. The screens are closely spaced from one another when the first and second syringe barrels are engaged with one another. The screens may take the form of a mesh, a plurality of protuberances, or cantilevered wedges having tapering thicknesses.

1 . A system for reconstituting and delivering solutions comprising:
 a first syringe barrel having an open proximal end and a male engagement region at a distal end, the male engagement region including a first screen;   a plunger received in the open proximal end of the first syringe barrel;   a second syringe barrel having an open proximal end and a female engagement region at a distal end, the female engagement region including a second screen; and   a plunger received in the open proximal end of the second syringe barrel,   the first syringe barrel and second syringe barrel being engageable with one another by engaging the male engagement region of the first syringe barrel with the female engagement region of the second syringe barrel.   
     
     
         2 . The system of  claim 1 , wherein the first syringe barrel includes a neck portion and the male engagement region includes a cylindrical inner wall and a cylindrical outer wall, each of the cylindrical inner and outer walls axially extending in a distal direction from the neck portion and defining a threaded channel therebetween. 
     
     
         3 . The system of  claim 2 , wherein the first screen extends radially inwardly from the cylindrical inner wall. 
     
     
         4 . The system of  claim 2 , wherein the second syringe barrel includes a neck portion and the female engagement region includes an axially extending cylindrical wall including at least one male thread on an outer surface thereof. 
     
     
         5 . The system of  claim 4 , wherein the second screen extends radially inwardly from the axially extending cylindrical wall of the second syringe barrel. 
     
     
         6 . The system of  claim 1 , wherein each of the first syringe barrel and second syringe barrel includes a pair of flanges projecting radially outwardly therefrom. 
     
     
         7 . The system of  claim 6 , wherein when the first syringe barrel and second syringe barrel are fully engaged with one another, the pair of flanges projecting radially from the first syringe barrel are substantially aligned with the pair of flanges projecting radially from the second syringe barrel. 
     
     
         8 . The system of  claim 1 , wherein at least one of the first and second screens is a mesh screen. 
     
     
         9 . The system of  claim 1 , wherein at least one of the first and second screens comprises a plurality of protuberances extending radially inwardly from a circular opening. 
     
     
         10 . The system of  claim 9 , wherein the protuberances are disposed at 45° intervals around the circular opening. 
     
     
         11 . The system of  claim 1 , wherein at least one of the first and second screens comprises a pair of bar-like elements arranged in a cross configuration. 
     
     
         12 . The system of  claim 1 , wherein at least one of the first and second screens comprises at least one cantilevered wedge. 
     
     
         13 . The system of  claim 12 , wherein the at least one cantilevered wedge is of a thickness that tapers from a perimeter of the screen toward a tip of the wedge. 
     
     
         14 . The system of  claim 12 , wherein the at least one of the first and second screens includes a plurality of cantilevered wedges radially spaced from one another, with each pair of adjacent cantilevered wedges defining a slot therebetween. 
     
     
         15 . The system of  claim 1 , wherein the first and second screens are spaced apart from one another by a distance in a range of approximately 0.02 inch to about 0.05 inch when the first syringe barrel and the second syringe barrel are fully engaged with one another. 
     
     
         16 . The system of  claim 1 , further comprising an adapter engageable with the female engagement region of the second syringe barrel. 
     
     
         17 . A method for reconstituting a powdered agent comprising:
 providing a first syringe barrel including a main chamber defined by a cylindrical barrel wall, an open proximal end, and a male engagement region at a distal end, the male engagement region including a screen;   providing a second syringe barrel including a main chamber defined by a cylindrical barrel wall, an open proximal end, and a female engagement region at a distal end, the female engagement region including a screen;   depositing the powdered agent into the main chamber of one of the first syringe barrel or the second syringe barrel; inserting a plunger in the open proximal end of the first syringe barrel;   inserting a plunger in the open proximal end of the second syringe barrel;   drawing a diluent into the main chamber of one of the first syringe barrel or the second syringe barrel;   engaging the male engagement region of the first syringe barrel with the female engagement region of the second syringe barrel; and   tilting the engaged first and second syringe barrels back and forth.   
     
     
         18 . The method of  claim 17 , wherein in providing the first syringe barrel, the first syringe barrel includes a neck portion and the male engagement region includes a cylindrical inner wall and a cylindrical outer wall, each of the cylindrical inner and outer walls axially extending in a distal direction from the neck portion and defining a threaded channel therebetween and the first screen extends radially inwardly from the cylindrical inner wall. 
     
     
         19 . The method of  claim 17 , wherein in providing the second syringe barrel, the second syringe barrel includes a neck portion, the female engagement region includes an axially extending cylindrical wall including at least one male thread on an outer surface thereof, and the second screen extends radially inwardly from the axially extending cylindrical wall of the second syringe barrel. 
     
     
         20 . The method of  claim 17 , wherein in providing each of the first syringe barrel and the second syringe barrel, each of the first syringe barrel and second syringe barrel includes a pair of flanges projecting radially outwardly therefrom, and in engaging the male engagement region of the first syringe barrel with the female engagement region of the second syringe barrel, substantially aligning the pair of flanges projecting radially from the first syringe barrel with the pair of flanges projecting radially from the second syringe barrel when the first syringe barrel and the second syringe barrel are fully engaged with one another. 
     
     
         21 . The method of  claim 17 , wherein in providing the first syringe barrel and the second syringe barrel, at least one of the first and second screens is a mesh screen. 
     
     
         22 . The method of  claim 17 , wherein in providing the first syringe barrel and the second syringe barrel, at least one of the first and second screens comprises a plurality of protuberances extending radially inwardly from a circular opening. 
     
     
         23 . The method of  claim 17 , wherein in providing the first syringe barrel and the second syringe barrel, at least one of the first and second screens comprises a pair of bar-like elements arranged in a cross configuration. 
     
     
         24 . The method of  claim 17 , wherein in providing the first syringe barrel and the second syringe barrel, at least one of the first and second screens comprises a plurality of cantilevered wedges radially spaced from one another, with each pair of adjacent cantilevered wedges defining a slot therebetween. 
     
     
         25 . The method of  claim 24 , wherein in tilting the engaged first and second syringe barrels back and forth, expanding the width of the slots between each pair of adjacent cantilevered wedges. 
     
     
         26 . The method of  claim 17 , further comprising, after tilting the engaged first and second syringe barrels back and forth:
 tilting the engaged first and second syringe barrels so that the mixed contents is disposed in the second syringe barrel;   disengaging the first and second syringe barrels; and   attaching an adapter to the female engagement region of the second syringe barrel.