Use of natural active substances in cosmetic or therapeutic compositions

Abstract

The invention relates to cosmetic or therapeutic compositions that contain hydrolysed yeast proteins as an active ingredient, to the use of said cosmetic or therapeutic compositions, and to a method for cosmetic treatment.

1 . A cosmetic or therapeutic composition comprising hydrolysed yeast proteins as active substance, wherein said hydrolysed yeast proteins are obtained from the insoluble fraction of yeast. 
     
     
         2 . The composition of  claim 1 , wherein the hydrolysed yeast proteins are obtained through enzymatic hydrolysis and/or acid hydrolysis and/or alkaline hydrolysis. 
     
     
         3 . The composition of  claim 1 , wherein the hydrolysed yeast proteins are obtained through enzymatic hydrolysis with at least a peptidase. 
     
     
         4 . The composition of  claim 1 , wherein the hydrolysed yeast proteins are obtained from yeast of a genus selected from the group consisting of  Saccharomyces, Kluyveromyces, Torula, Candida, Hansenula, Pichia,  and mixtures thereof. 
     
     
         5 . The composition of  claim 1 , wherein the hydrolysed yeast proteins comprise at least 40% of yeast proteins with a molecular weight ranging from 1 to 5 kDa. 
     
     
         6 . The composition of  claim 1 , wherein the hydrolysed yeast proteins comprise at most 55% of hydrolysed yeast proteins with a molecular weight lower than 1 kDa. 
     
     
         7 . The composition of  claim 1 , wherein the AN/TN ratio of the hydrolysed yeast proteins is lower than or equal to 35%. 
     
     
         8 . The composition of  claim 1 , comprising from 0.001% to 20% of hydrolysed yeast proteins. 
     
     
         9 . The composition of  claim 1 , comprising at least one additive selected from the group consisting of preservatives, chelating agents, colouring agents, UV filters, pH regulators, texturising agents, perfumes and antioxidants. 
     
     
         10 . A method of preparation of a cosmetic or therapeutic composition, comprising the following steps:
 hydrolysing proteins of the insoluble fraction of yeast in order to obtain hydrolysed yeast proteins, and   mixing said hydrolysed yeast proteins with an acceptable cosmetic or therapeutic vehicle.   
     
     
         11 . (canceled) 
     
     
         12 . A method of cosmetic treatment comprising a step of contacting the composition of  claim 1  with the skin and/or skin appendages and/or mucous membranes. 
     
     
         13 . The method of cosmetic treatment of  claim 12  intended to moisturise the skin and/or mucous membranes and/or skin appendages, and/or improve the repair of the skin and/or mucous membranes and/or skin appendages, and/or improve dermis firmness, and/or fight against skin aging, and/or regulate sebum secretion, and/or reduce dandruff. 
     
     
         14 . Hydrolysed yeast proteins obtained from the insoluble fraction of yeast for use as a medicament. 
     
     
         15 . The composition of  claim 1 , wherein the hydrolysed yeast proteins are obtained from yeast of  Saccharomyces.    
     
     
         16 . The composition of  claim 1 , wherein the hydrolysed yeast proteins are obtained from yeast of  Saccharomyces cerevisiae.    
     
     
         17 . The composition of  claim 1 , comprising at least one excipient selected from the group consisting of hydrophilic compounds, hydrophobic compounds and surfactants. 
     
     
         18 . A method of cosmetic: treatment comprising a step of contacting a composition obtainable through the process according to  claim 10  with the skin and/or skin appendages and/or mucous membranes. 
     
     
         19 . Hydrolysed yeast proteins according to  claim 14 , wherein the medicament is for the treatment and/or prevention of pathological dry skin, pathological healing problems and/or pathological hyperseborrhoea and/or acne. 
     
     
         20 . The composition of  claim 1 , wherein the hydrolysed yeast proteins comprise at least 60% of yeast proteins with a molecular weight ranging from 1 to 5 kDa. 
     
     
         21 . The composition of  claim 1 , wherein the hydrolysed yeast proteins comprise at most 35% of hydrolysed yeast proteins with a molecular weight lower than 1 kDa. 
     
     
         22 . The composition of  claim 1 , wherein the AN/TN ratio of the hydrolysed yeast proteins is lower than or equal to 20%. 
     
     
         23 . The composition of  claim 1 , comprising from 0.01% to 2% of hydrolysed yeast proteins. 
     
     
         24 . The composition of  claim 3 , wherein the peptidase is selected from the group consisting of papain, trypsin, chymotrypsin, subtilisin, pepsin, thermolysin, pronase, flavastacine, enterokinase, factor Xa protease, furin, bromelain, proteinase K, genenase I, thermitase, carboxypeptidase A, carboxypeptidase B, collagenase, and mixtures thereof.