US2011009284A1PendingUtilityA1

Gene relating to estimation of postoperative prognosis for breast cancer

Assignee: MITSUBISHI RAYON COPriority: Feb 24, 2004Filed: May 21, 2010Published: Jan 13, 2011
Est. expiryFeb 24, 2024(expired)· nominal 20-yr term from priority
G01N 33/57515C12Q 2600/118C12Q 1/6886
45
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Claims

Abstract

It is intended to provide a system of predicting the postoperative prognosis in a patient with breast cancer from the viewpoint of gene expression based on the data obtained by genome-wide and comprehensive analysis on gene expression in breast cancer. Expression of human genes is comprehensively analyzed by using a DNA microarray and gene expression functions in various breast cancer conditions are compared, thereby establishing a system of predicting the postoperative prognosis of breast cancer.

Claims

exact text as granted — not AI-modified
1 - 19 . (canceled) 
     
     
         20 . A method for predicting a postoperative prognosis in node-negative (n0) breast cancer with no metastasis to a lymph node in operation, comprising measuring an expression of galectin 1 gene. 
     
     
         21 . The method of  claim 20 , wherein the measurement is performed by using galectin 1 gene and/or a probe specific thereto. 
     
     
         22 . The method of  claim 21 , wherein the galactin 1 gene/and or the probe are carried on a DNA microarray. 
     
     
         23 . The method of  claim 22 , wherein the DNA microarray is a fiber type array. 
     
     
         24 . The method of  claim 21 , wherein the measurement is performed using the galectin 1 gene. 
     
     
         25 . The method of  claim 21 , wherein the measurement is performed using the probe to the galectin 1 gene and the galectin 1 gene. 
     
     
         26 . The method of  claim 22 , wherein the galectin 1 gene is carried on the DNA microarray. 
     
     
         27 . The method of  claim 22 , wherein the probe specific to the galectin 1 gene is carried on the DNA microarray. 
     
     
         28 . The method of  claim 22 , wherein the galectin 1 gene and the probe specific to the galectin 1 gene are carried on the DNA microarray.

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