US2011008271A1PendingUtilityA1

Rosacea treatments using polymetal complexes

Assignee: JR CHEM LLCPriority: Jul 13, 2009Filed: Jul 7, 2010Published: Jan 13, 2011
Est. expiryJul 13, 2029(~3 yrs left)· nominal 20-yr term from priority
A61K 8/362A61K 2800/884A61Q 19/00A61K 31/4164A61K 31/315A61K 8/671A61K 2800/88A61K 45/06A61K 31/60A61Q 19/10A61K 31/59A61K 8/27A61Q 17/04A61K 31/415A61K 33/30A61K 8/67A61K 31/235A61K 31/07
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Claims

Abstract

Described herein are novel methods for the treatment of rosacea which include the step of applying of a composition containing a polymetal complex to an area of the skin afflicted with rosacea and novel regimens using such compounds.

Claims

exact text as granted — not AI-modified
1 . A treatment regimen comprising:
 cleansing at least a portion of an area of skin afflicted with rosacea with an antimicrobial or cleanser;   applying a composition containing a polymetal complex to at least a portion of the cleansed area; and   applying a protective composition to at least a portion of the cleansed, and polymetal complex-treated area.   
     
     
         2 . A treatment regimen as in  claim 1  further comprising the step of applying a composition containing metronidazole to at least a portion of the afflicted area. 
     
     
         3 . A treatment regimen as in  claim 1  further comprising the step of applying an anti-redness composition to at least a portion of the afflicted area. 
     
     
         4 . A treatment regimen as in  claim 1  further comprising the step of applying an anti-parasitic compound to at least a portion of the afflicted area. 
     
     
         5 . The treatment regimen of  claim 4  wherein the anti parasitic product is selected from the group consisting of benzyl benzoate, salicylic acid and combinations thereof. 
     
     
         6 . A treatment regimen as in  claim 1  wherein the polymetal complex comprises a Cu/Zn malonate complex. 
     
     
         7 . A treatment regimen as in  claim 1  wherein the protective composition comprises a sunscreen. 
     
     
         8 . A treatment regimen as in  claim 1  wherein the protective composition comprises a compound selected from the group consisting of ZnO, Vitamin A, Vitamin D and combinations thereof. 
     
     
         9 . A treatment regimen as in  claim 1  further comprising the step of applying a benzoyl peroxide containing composition to at least a portion of the cleansed, and moisturized area of skin. 
     
     
         10 . A treatment regimen as in  claim 1  further comprising the step of applying a retinoid containing composition to at least a portion of the cleansed, moisturized area of skin. 
     
     
         11 . A treatment regimen as in  claim 1  further comprising the step of applying an antibiotic containing composition to at least a portion of the cleansed, and moisturized area of skin. 
     
     
         12 . The treatment method of  claim 1  further comprising the step of taking an oral antibiotic after applying the protective composition. 
     
     
         13 . A kit comprising:
 a cleanser;   a composition containing a polymetal complex; and   a protective composition.   
     
     
         14 . A kit as in  claim 13  further comprising a composition containing metronidazole. 
     
     
         15 . A kit as in  claim 13  further comprising a composition containing an anti-redness composition. 
     
     
         16 . A kit as in  claim 13  further comprising a composition containing an antibiotic. 
     
     
         17 . A kit as in  claim 13  further comprising an anti-parasitic composition. 
     
     
         18 . A kit as in  claim 13  wherein the composition containing a polymetal complex is a moisturizing composition. 
     
     
         19 . A kit as in  claim 13  wherein the protective composition is a sunscreen containing vitamins A and D. 
     
     
         20 . A method of treating skin afflicted with rosacea comprising the step of applying a redness reducing amount of a composition containing a polymetal complex to at least a portion of the afflicted area. 
     
     
         21 . The method of  claim 20  wherein the polymetal complex is a Cu/Zn malonate complex. 
     
     
         22 . The method of  claim 12  wherein the a composition containing a polymetal complex further includes a moisturizer. 
     
     
         23 . The method of  claim 20  further comprising the step of cleansing at least a portion of the afflicted area. 
     
     
         24 . The method of  claim 23  wherein the cleanser is an antimicrobial cleanser. 
     
     
         25 . The method of  claim 24  wherein the antimicrobial cleanser is selected from the group consisting of chlorhexidine gluconate, triclosan, zinc pyrithione, clindamycin phosphate, sodium sulphacetamide and combinations thereof. 
     
     
         26 . The method of  claim 20  further comprising the step of applying a protective composition to at least a portion of the afflicted area 
     
     
         27 . The method of  claim 26  wherein the protective composition comprises a sunscreen. 
     
     
         28 . The method of  claim 27  wherein the sunscreen comprises a compound selected from the group consisting of ZnO, Vitamin A, Vitamin D and combinations thereof. 
     
     
         29 . The method of claim of  claim 20  further comprising the step of applying an anti-parasitic product to at least a portion of the afflicted area. 
     
     
         30 . The method of  claim 29  wherein the anti-parasitic product includes a compound selected from the group consisting of benzyl benzoate, salicyclic acid and combinations thereof. 
     
     
         31 . The method of  claim 20  further comprising the step of applying an additional an anti-acne medication to at least a portion of the afflicted area. 
     
     
         32 . The method of  claim 31  wherein the anti-acne medication is selected from the group consisting of benzoyl peroxide, retinoids, tetracycline, clindamycin, erythromycin, and combinations thereof.

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