US2011003293A1PendingUtilityA1

Fetal aneuploidy detection by sequencing

Assignee: ARTEMIS HEALTH INCPriority: Jun 14, 2006Filed: Mar 31, 2010Published: Jan 6, 2011
Est. expiryJun 14, 2026(expired)· nominal 20-yr term from priority
C12Q 1/6883C12Q 2600/156C12Q 1/6874
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Claims

Abstract

The present invention provides apparatus and methods for enriching components or cells from a sample and conducting genetic analysis, such as SNP genotyping to provide diagnostic results for fetal disorders or conditions.

Claims

exact text as granted — not AI-modified
1 . A method for detecting fetal abnormality comprising:
 determining a ratio of abundance of maternal allele(s) to abundance of paternal allele(s) in genomic DNA from fetal cells enriched from a maternal blood sample using size-based separation.

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