Bacterial strain having anti-allergic activity, and beverage, food and anti-allergic agent comprising cell of the bacterial strain

Abstract

It is an object of the present invention to provide a bacterial strain belonging to Lactobacillus brevis subspecies brevis , which has more potent antiallergic activity than the known lactic acid bacteria strains and produces γ-aminobutyric acid (GABA). It is another object of the present invention to provide beverages and foods containing cells of the aforementioned bacterial strain belonging to Lactobacillus brevis subspecies brevis , as well as antiallergic agents containing them as an active ingredient. The present invention provides a bacterial strain belonging to Lactobacillus brevis subspecies brevis , which: is capable of growing in effervescent alcoholic beverages, produces γ-aminobutyric acid (GABA), and has antiallergic activity.

1 . A bacterial strain belonging to  Lactobacillus brevis  subspecies  brevis , which:
 is capable of growing in effervescent alcoholic beverages,   produces γ-aminobutyric acid (GABA), and   has antiallergic activity.   
     
     
         2 . The bacterial strain according to  claim 1 , wherein the antiallergic activity is activity which promotes the production of at least one of interferon γ and interleukin 12. 
     
     
         3 . The bacterial strain according to  claim 1 , wherein the antiallergic activity is activity which inhibits the production of IgE. 
     
     
         4 . The bacterial strain according to  claim 1 , which is SBC8803 (FERM BP-10632) belonging to  Lactobacillus brevis  subspecies  brevis.    
     
     
         5 . A beverage comprising cells of the bacterial strain according to  claim 1 . 
     
     
         6 . A food comprising cells of the bacterial strain according to  claim 1 . 
     
     
         7 . An antiallergic agent comprising cells of the bacterial strain according to  claim 1  as an active ingredient. 
     
     
         8 . The bacterial strain according to  claim 2 , which is SBC8803 (FERM BP-10632) belonging to  Lactobacillus brevis  subspecies  brevis.    
     
     
         9 . The bacterial strain according to  claim 3 , which is SBC8803 (FERM BP-10632) belonging to  Lactobacillus brevis  subspecies  brevis.    
     
     
         10 . A beverage comprising cells of the bacterial strain according to  claim 2 . 
     
     
         11 . A beverage comprising cells of the bacterial strain according to  claim 3 . 
     
     
         12 . A beverage comprising cells of the bacterial strain according to  claim 4 . 
     
     
         13 . A food comprising cells of the bacterial strain according to  claim 2 . 
     
     
         14 . A food comprising cells of the bacterial strain according to  claim 3 . 
     
     
         15 . A food comprising cells of the bacterial strain according to  claim 4 . 
     
     
         16 . An antiallergic agent comprising cells of the bacterial strain according to  claim 2  as an active ingredient. 
     
     
         17 . An antiallergic agent comprising cells of the bacterial strain according to  claim 3  as an active ingredient. 
     
     
         18 . An antiallergic agent comprising cells of the bacterial strain according to  claim 4  as an active ingredient.