US2010330061A1PendingUtilityA1

Methods and Devices for Treating Lung Dysfunction

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Individually held — no corporate assignee on recordPriority: May 15, 2001Filed: Jul 2, 2010Published: Dec 30, 2010
Est. expiryMay 15, 2021(expired)· nominal 20-yr term from priority
Inventors:Gregory Conner
A61P 31/10A61P 31/04A61P 31/12A61K 31/00A61K 33/00A61P 11/00A61K 33/40A61K 9/0073
32
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Claims

Abstract

Methods and devices useful for treatment of lung conditions resulting from dysfunction of normal pulmonary physiology.

Claims

exact text as granted — not AI-modified
1 . A method of treating a lung condition in a primate exhibiting symptoms of cystic fibrosis, said method comprising administering to the respiratory system of said primate an effective amount of H 2 O 2 . 
     
     
         2 . The method of  claim 1 , wherein said administering is by inhalation of H 2 O 2 . 
     
     
         3 . The method of  claim 1 , wherein said administering is a formulation which produces H 2 O 2  in said respiratory system. 
     
     
         4 . The method of  claim 1 , wherein said lung condition comprises infection with a:
 a) bacterium, including  Staphylococcus aureus, Pseudomonas aeruginosa,  or  Burkholderia cepacia;      b) fungus; or   c) virus.   
     
     
         5 . The method of  claim 1 , wherein said administering is in combination with:
 a) administering a peroxidase; or   b) administering thiocyanate.   
     
     
         6 . The method of  claim 1 , wherein said administering is in combination with a treatment for a lung condition, including a lung infection or cystic fibrosis. 
     
     
         7 . The method of  claim 6 , wherein said additional treatment comprises administering an:
 a) an antibiotic;   b) anti-fungal; or   c) anti-viral.   
     
     
         8 . The method of  claim 6 , wherein said additional treatment comprises:
 a) administering an enzyme, including a depolymerase; or   b) an airway clearance technique or physical therapy, including breathing exercises, postural drainage, chest percussion, vibration, or assisted coughing.   
     
     
         9 . The method of  claim 1 , wherein said H 2 O 2  is:
 a) at a concentration between 10 −7  M and 10 −4  M in the lung fluid; or   b) is administered between once in a week to hourly.   
     
     
         10 . A method of treating a lung infection in a mammal, said method comprising administering to the respiratory system of said mammal an effective amount of H 2 O 2 . 
     
     
         11 . The method of  claim 10 , wherein said administering is by inhalation of H 2 O 2 . 
     
     
         12 . The method of  claim 10 , wherein said administering is a formulation which produces H 2 O 2  in said respiratory system. 
     
     
         13 . The method of  claim 10 , wherein said lung infection comprises a:
 a) bacterium, including  Staphylococcus aureus, Pseudomonas aeruginosa,  or  Burkholderia cepacia;      b) fungus; or   c) virus.   
     
     
         14 . The method of  claim 10 , wherein said administering is in combination with:
 a) peroxidase; or   b) thiocyanate.   
     
     
         15 . The method of  claim 10 , wherein said administering is in combination with an additional treatment for a lung condition, including a lung infection or cystic fibrosis. 
     
     
         16 . The method of  claim 15 , wherein said additional treatment comprises administering an:
 a) antibiotic;   b) anti-fungal; or   c) anti-viral,   
     
     
         17 . The method of  claim 15 , wherein said additional treatment comprises:
 a) administering an enzyme, including a depolymerase; or   b) an airway clearance technique or physical therapy, including breathing exercises, postural drainage, chest percussion, vibration, or assisted coughing.   
     
     
         18 . The method of  claim 10 , wherein said H 2 O 2  is:
 a) at a concentration between 10 −7  M and 10 −4  M in the lung fluid; or   b) is administered between once in a week to hourly.   
     
     
         19 . An inhaler comprising:
 a) hydrogen peroxide;   b) a peroxidase; or   c) thiocyanate.   
     
     
         20 . The inhaler of  claim 19 , further comprising an antibiotic, an anti-fungal, or an anti-vial.

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