Pharmaceutical Compositions

Abstract

The present invention relates to an improved mode of administration for cannabis and its natural and synthetic derivatives. A pharmaceutical composition suitable for sublingual aerosol or spray delivery of cannabis is provided. The formulation may be dispensed using a pump spray or the formulation may include a propellant, such as butane, 1,1,1,2-tetrafluoroethane (HFC-134a) or 1,1,1,2,3,3,3-heptafluoropropane (HFC-227). The term cannabis is used herein to refer to all physiologically active substances derived from the cannabis family of plants and synthetic cannabis analogues and derivatives, precursors, metabolites etc., or related substances having cannabis-like physiological effects.

1 . A method of cannabis delivery comprising:
 administering cannabis to a patient sublingually in aerosol or spray form, wherein the cannabis is a liquid extract derived from a cannabis plant delivered from a pump spray device which is adapted to dispense particles of a size and at a velocity that optimizes sublingual uptake to the sublingual mucosa.   
     
     
         2 . The method as claimed in  claim 1 , further comprising administering at least one carrier. 
     
     
         3 . The method as claimed in  claim 2 , wherein the at least one carrier is ethanol. 
     
     
         4 . The method as claimed in  claim 2 , wherein the at least one carrier is propylene glycol. 
     
     
         5 . The method as claimed in  claim 2 , wherein a plurality of carriers is administered. 
     
     
         6 . The method as claimed in  claim 5  wherein the plurality of carriers comprise ethanol and propylene glycol. 
     
     
         7 . The method as claimed in  claim 1 , further comprising a flavoring oil.