Composition for inhibition of transplant rejection containing the cordyceps mycellia extract as an active ingredient

Abstract

Disclosed is a composition for the inhibition of transplant rejection and the prevention and treatment of skin diseases, comprising a cordyceps mycellia extract as an active ingredient. The cordyceps mycellia extract significantly suppresses the production of antibodies to transplants without side effects, such as weight change. Based on natural material, the composition is non-toxic and harmless to the human body and thus can be used as an immunosuppressant for organ transplantation. Also, it stops oozing from sores and is useful in the prevention and treatment of skin diseases, including atopy, allergic reactions, decubitus ulcers, pemphigus and smallpox.

1 . An immunosuppressive composition for inhibition of transplant injection, comprising a mycelial extract from vegetable worm as an active ingredient. 
     
     
         2 . The immunosuppressive composition according to  claim 1 , wherein the vegetable worm is one selected from a group consisting of  Cordyceps militaris, Cordyceps sinensis, Hymenostilbe odonatae, Cordyceps nutans, Tilachlidiopsis nigra, Paecilomyces japonica, Cordyceps tricentri  and  Cordyceps sphecocephala . 
     
     
         3 . The immunosuppressive composition according to  claim 1 , wherein the composition is in a dosage form suitable for oral, intravenous or abdominal administration. 
     
     
         4 . The immunosuppressive composition according to  claim 3 , wherein the composition is orally administered at a dose from 550 to 2,200 mg/day. 
     
     
         5 . The immunosuppressive composition according to  claim 1 , wherein the composition suppresses production of antibodies after organ or tissue transplantation, said antibodies causing transplant rejection. 
     
     
         6 . A composition for prevention and treatment of skin diseases, comprising a  cordyceps  mycellia extract as an active ingredient. 
     
     
         7 . The composition according to  claim 6 , wherein the skin diseases are atopy, decubitus ulcer, pemphigus and/or smallpox.