Compositions containing chalcones and use thereof

Abstract

The present invention features composition comprising a chalcone and the use thereof for treating acne and reducing the appearance of oil or pores on the skin, hair and scalp.

1 . A composition comprising: (a) a green tea extract comprising at least one catechin, and (b) at least one chalcone selected from the group consisting of chalcones of the formulae: 
       
         
           
           
               
               
           
         
       
       and enantiomers, diastereomers, and cosmetically-acceptable salts thereof. 
     
     
         2 . The composition of  claim 1  wherein said at least one chalcone comprises 2′-hydroxy-2,3,5′-trimethoxychalcone, 2,2′-dyhydroxychalcone, or an enantiomer, diastereomer, or cosmetically acceptable salt thereof. 
     
     
         3 . The composition of  claim 1  further comprising salicylic acid or benzoyl peroxide. 
     
     
         4 . The composition of  claim 1  wherein said green tea extract is present in an amount of 0.1 to 10% by weight of the composition. 
     
     
         5 . The composition of  claim 1  wherein said catechin is selected from the group consisting of catechin, catechin gallate, epicatechin, gallocatechin, gallocatechin gallate, epigallocatechin, epicatechin gallate, and epigallocatechin gallate. 
     
     
         6 . The composition of  claim 1  wherein said at least one chalcone comprises 2,2′-dyhydroxychalcone, or an enantiomer, diastereomer, or cosmetically acceptable salt thereof and said green tea extract was extracted using a solvent comprising water. 
     
     
         7 . A method of treating acne or reducing the appearance of oil or pores on the skin, said method comprising administering to skin in need of such treatment a composition of  claim 1 . 
     
     
         8 . A method of treating acne or reducing the appearance of oil or pores on the skin, said method comprising administering to skin in need of such treatment a composition of  claim 2 . 
     
     
         9 . A method of treating acne or reducing the appearance of oil or pores on the skin, said method comprising administering to skin in need of such treatment a composition of  claim 6 .