Novel botanical formulation for treating sickle cell disease

Abstract

An improved plant medicament composition, comprising an extract of Sorghum bicolor plant material for treating sickle cell disease is described. A method for the preparation of said composition having the property of inhibiting sickle cells is also provided.

1 . A botanical composition for inhibiting sickling in sickle cell disease, comprising an extraction from  Sorghum bicolor  plant material, without using material from any other plant, said extraction being effective against sickle cells. 
     
     
         2 . The composition of  claim 1  further comprising any pharmaceutically acceptable carrier and excipients. 
     
     
         3 . The composition of  claim 2 , wherein said extraction is formulated as a solution, suspension, powder, tablet or capsule. 
     
     
         4 . A method for preparing a botanical composition, comprising the steps of:
 (i) obtaining an extract having anti-sickling activity from  Sorgum bicolor  plant material; and   (ii) preparing said extract in a suitable form for treating sickle cells.   
     
     
         5 . The method of  claim 4 , comprising the steps of:
 (i) extracting  Sorghum bicolor  plant material with a 7.4% weight by volume aqueous solution of sodium bicarbonate at a pH ranging from about 8.0 to about 8.3 by stirring for about 8 hr at normal ambient temperature;   (ii) allowing the extract to settle, then decanting, filtering, centrifuging and freeze drying the resulting material; and   (iii) thoroughly blending the freeze dried material to form a uniform mixture.   
     
     
         6 . The method of  claim 5 , further comprising any pharmaceutically acceptable carrier and excipients. 
     
     
         7 . The method of  claim 6 , administering said blended uniform mixture for treating sickle cell disease in a powder, tablet, capsule, granular or suspension form.