US2010249205A1PendingUtilityA1

Metabolites of Wortmannin Analogs and Methods of Using Same

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Assignee: UNIV ARIZONAPriority: Dec 30, 2005Filed: Apr 1, 2010Published: Sep 30, 2010
Est. expiryDec 30, 2025(expired)· nominal 20-yr term from priority
Inventors:Garth Powis
A61P 35/00C07D 311/94
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PatentIndex Score
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Claims

Abstract

Novel metabolites of wortmannin and wortmannin analogs and their use in inhibiting PI-3 kinase activity in mammals and the treatment and prevention of cancer or tumor formation in a subject are described herein.

Claims

exact text as granted — not AI-modified
1 . A compound selected from: 
       
         
           
           
               
               
           
         
         
           
           
               
               
           
         
       
     
     
         2 - 21 . (canceled) 
     
     
         22 . A composition comprising a compound of formula 
       
         
           
           
               
               
           
         
       
       and a carrier. 
     
     
         23 . A method of treating colon cancer comprising administering to an individual in need thereof a therapeutically effective amount of a composition of  claim 22 .

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