US2010234578A1PendingUtilityA1

Anti-cd40 monoclonal antibody

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Assignee: KYOWA HAKKO KIRIN CO LTDPriority: Apr 27, 2001Filed: Mar 23, 2010Published: Sep 16, 2010
Est. expiryApr 27, 2021(expired)· nominal 20-yr term from priority
Inventors:Toshifumi MikayamaHitoshi YoshidaWalker R. ForceXingjie ChenNobuaki Takahashi
A61P 37/06A61K 2039/505A61P 37/04C07K 2319/00A61P 7/00A61P 37/08C07K 2319/30C07K 16/2878A61P 37/02A61P 7/04C07K 2317/21A61P 35/00
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Claims

Abstract

An antibody or a functional fragment thereof, acting agonistically or antagonistically on CD40.

Claims

exact text as granted — not AI-modified
1 .- 30 . (canceled) 
     
     
         31 . An antibody or a functional fragment thereof, having the amino acid sequences of a heavy chain variable region and a light chain variable region of an antibody that is produced by, 2105 (Accession No: FERM BP-8024) or F1-102 (Accession No: ATCC PTA-3337). 
     
     
         32 - 34 . (canceled) 
     
     
         35 . An antibody or a functional fragment thereof, having amino acid sequences of a heavy chain variable region and a light chain variable region of the antibody produced by a hybridoma 2053 or 285. 
     
     
         36 . An antibody or a functional fragment thereof, having amino acid sequences of a heavy chain variable region and a light chain variable region of the antibody produced by a hybridoma KM281-1-10 (Accession No: FERM BP-7579), 4D11 (Accession No: FERM BP-7758). 
     
     
         37 - 44 . (canceled)

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