Production process of film and column for cation chromatography

Abstract

One object of the present invention is to produce a weakly acidic cation exchanger under mild conditions. Another object of the present invention is to produce a more firm weakly acidic cation exchange film. Still another object of the present invention is to provide a weakly acidic cation exchanger capable of realizing high-level separation of monovalent cation and simultaneously analyzing monovalent cation and divalent cation and also provide a chromatography column using the ion exchanger. In the production method of a weakly acidic cation exchanger of the invention, a solvent incapable of dissolving a polymer having a double bond within the molecule is used and the weakly acidic cation exchanger is produced by polymerization at temperature of 100° C. or less.

1 . A film production process comprising the following steps (1) and (2):
 Step (1):
 a step of coating a polymer having a double bond within the molecule on a support, wherein the polymer having a double bond within the molecule is an unsaturated carboxylic acid-diene monomer copolymer and/or an unsaturated carboxylic anhydride-diene monomer copolymer, 
   Step (2):
 a step of placing the support coated with the polymer in a solvent incapable of dissolving the polymer coated, to cause a crosslinking reaction of the double bond within the molecule by means of radical polymerization initiators and thereby form a film. 
   
   
   
       2 . A film production process comprising the following steps (1) and (2):
 Step (1):
 a step of coating a polymer having a double bond within the molecule on a support, wherein the polymer having a double bond within the molecule is a poly(butadiene-maleic acid) and/or a poly(butadiene-maleic anhydride) 
   Step (2):
 a step of placing the support coated with the polymer in a solvent incapable of dissolving the polymer coated, to cause a crosslinking reaction of the double bond within the molecule by means of radical polymerization initiators and thereby form a film. 
   
   
   
       3 . The film production process as claimed in  claim 1 , wherein the support is a spherical porous particle having a particle size of 1 to 30 μm. 
   
   
       4 . The film production process as claimed in  claim 2 , wherein the support is a spherical porous particle having a particle size of 1 to 30 μm. 
   
   
       5 . The film production process as claimed in  claim 3 , wherein the spherical porous particle is a silica gel or a polyvinyl ether gel. 
   
   
       6 . The film production process as claimed in  claim 4 , wherein the spherical porous particle is a silica gel or a polyvinyl ether gel. 
   
   
       7 . The film production process as claimed in  claim 1 , wherein the film is a weakly acidic cation exchanger. 
   
   
       8 . The film production process as claimed in  claim 2 , wherein the film is a weakly acidic cation exchanger. 
   
   
       9 . A film produced by the production process in  claim 1 . 
   
   
       10 . A film produced by the production process in  claim 2 . 
   
   
       11 . A weakly acidic cation exchanger produced by the production process in  claim 1 . 
   
   
       12 . A weakly acidic cation exchanger produced by the on process in  claim 2 . 
   
   
       13 . A column for cation chromatography, using the weakly acidic cation exchange of  claim 11 . 
   
   
       14 . A column for cation chromatography, using the weakly acidic cation exchange of  claim 12 .