US2010216981A1PendingUtilityA1

Antiviral agent

52
Assignee: NIPPON SODA COPriority: Mar 23, 2007Filed: Mar 19, 2008Published: Aug 26, 2010
Est. expiryMar 23, 2027(~0.7 yrs left)· nominal 20-yr term from priority
Inventors:Shinsuke SanoTakako FukagawaHirokazu YamadaChikara MasutaHanako Shimura
A61P 31/16A61P 43/00A61K 31/122A61P 31/22A61K 31/7105A61P 31/20A61K 31/7088A61P 31/18A61P 31/12
52
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

An object of the present invention is to provide a viral disease control agent which has a mechanism of action different from conventional one as a substitute for existing viral disease control methods and is used in more practical and safer manners. The present invention utilizes a compound having inhibitory activity on the binding of a substance α to a PTGS suppressor protein, wherein the substance α has a property of inducing PTGS and a property of binding to the PTGS suppressor protein and shows a decrease in the property of inducing PTGS upon binding to the PTGS suppressor protein.

Claims

exact text as granted — not AI-modified
1 . A PTGS suppressor protein binding inhibitor containing a compound having inhibitory activity on the binding of a substance α to a PTGS suppressor protein, wherein the substance α has a property of inducing PTGS and a property of binding to the PTGS suppressor protein and shows a decrease in the property of inducing PTGS upon binding to the PTGS suppressor protein. 
     
     
         2 . The PTGS suppressor protein binding inhibitor according to  claim 1 , wherein the substance α is siRNA. 
     
     
         3 . The PTGS suppressor protein binding inhibitor according to  claim 1 , wherein the compound is at least one selected from the group consisting of cyclic ketone compounds represented by the following formulas (1) to (6): 
       
         
           
           
               
               
           
         
       
     
     
         4 . The PTGS suppressor protein binding inhibitor according to  claim 1 , wherein the compound is a reaction product of croconic acid with hydrogen peroxide. 
     
     
         5 . An antiviral agent comprising, as an active ingredient, a compound having inhibitory activity on the binding of a substance α to a PTGS suppressor protein, wherein the substance α has a property of inducing PTGS and a property of binding to the PTGS suppressor protein and shows a decrease in the property of inducing PTGS upon binding to the PTGS suppressor protein. 
     
     
         6 . The antiviral agent according to  claim 5 , wherein the substance α is siRNA. 
     
     
         7 . The antiviral agent according to  claim 5 , wherein the compound is at least one selected from the group consisting of cyclic ketone compounds represented by the following formulas (1) to (6): 
       
         
           
           
               
               
           
         
       
     
     
         8 . The antiviral agent according to  claim 5 , wherein the compound is a reaction product of croconic acid with hydrogen peroxide. 
     
     
         9 . The PTGS suppressor protein binding inhibitor according to  claim 2 , wherein the compound is at least one selected from the group consisting of cyclic ketone compounds represented by the following formulas (1) to (6): 
       
         
           
           
               
               
           
         
       
     
     
         10 . The PTGS suppressor protein binding inhibitor according to  claim 2 , wherein the compound is a reaction product of croconic acid with hydrogen peroxide. 
     
     
         11 . The antiviral agent according to  claim 6 , wherein the compound is at least one selected from the group consisting of cyclic ketone compounds represented by the following formulas (1) to (6): 
       
         
           
           
               
               
           
         
       
     
     
         12 . The antiviral agent according to  claim 6 , wherein the compound is a reaction product of croconic acid with hydrogen peroxide.

Join the waitlist — get patent alerts

Track US2010216981A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.