US2010196508A1PendingUtilityA1

Method and composition for supplementation of nutritional deficiencies in renal patients

43
Individually held — no corporate assignee on recordPriority: Sep 27, 2000Filed: Apr 12, 2010Published: Aug 5, 2010
Est. expirySep 27, 2020(expired)· nominal 20-yr term from priority
Inventors:John A. GiordanoCharles Balzer
A61P 3/02A61P 13/12A61K 31/525A61K 31/714A61K 31/355A23L 33/16A61K 31/51A23L 33/15A23V 2002/00A61K 33/32
43
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The present invention relates to compositions and methods for treating the nutritional deficiencies observed in patients suffering from renal disease and associated disorders. Specifically, the method involves administering to a renal patient a composition comprising vitamin C, vitamin E, B-complex vitamins, selenium, and zinc.

Claims

exact text as granted — not AI-modified
1 . A composition for supplementing nutritional deficiencies in a patient or person in need thereof, comprising about 60 mg to about 140 mg vitamin C; about 40 IU to about 80 IU vitamin E; about 1.5 mg to about 4.5 mg vitamin B 1 ; about 1 mg to about 3 mg vitamin B 2 ; about 10 mg to about 30 mg vitamin B 3 ; about 5 mg to about 15 mg vitamin B 5 ; about 18 mg to about 42 mg vitamin B 6 ; about 500 μg to about 1500 μg vitamin B 12 ; about 150 μg to about 450 μg biotin; about 3 mg to about 8 mg vitamin B 9 ; about 35 μg to about 105 μg selenium; and about 10 mg to about 30 mg zinc. 
   
   
       2 . A composition for supplementing nutritional deficiencies in a patient or person in need thereof, comprising about 80 mg to about 120 mg vitamin C; about 48 IU to about 72 IU vitamin E; about 2.4 mg to about 3.6 mg vitamin B 1 ; about 1.6 mg to about 2.4 mg vitamin B 2 ; about 16 mg to about 24 mg vitamin B 3 ; about 8 mg to about 12 mg vitamin B 5 ; about 24 mg to about 36 mg vitamin B 6 ; about 800 μg to about 1200 μg vitamin B 12 ; about 240 μg to about 360 μg biotin; about 4.4 mg to about 6.6 mg vitamin B 9 ; about 56 μg to about 84 μg selenium; and about 16 mg to about 24 mg zinc. 
   
   
       3 . A composition for supplementing nutritional deficiencies in a patient or person in need thereof, comprising about 90 mg to about 110 mg vitamin C; about 54 Hi to about 66 IU vitamin E; about 2.7 mg to about 3.3 mg vitamin B 1 ; about 1.8 mg to about 2.2 mg vitamin B 2 ; about 18 mg to about 22 mg vitamin B 3 ; about 9 mg to about 11 mg vitamin B 5 ; about 27 mg to about 33 mg vitamin B 6 ; about 900 μg to about 1100 μg vitamin B 12 ; about 270 μg to about 330 μg biotin; about 4.95 mg to about 6.05 mg vitamin B 9 ; about 63 μg to about 77 μg selenium; and about 18 mg to about 22 mg zinc. 
   
   
       4 . The composition of  claim 1 , wherein said composition comprises about 100 mg vitamin C. 
   
   
       5 . The composition of  claim 1 , wherein said composition comprises about 60 IU vitamin E. 
   
   
       6 . The composition of  claim 1 , wherein said composition comprises about 3 mg vitamin B 1 . 
   
   
       7 . The composition of  claim 1 , wherein said composition comprises about 2 mg vitamin B 2 . 
   
   
       8 . The composition of  claim 1 , wherein said composition comprises about 20 mg vitamin B 3 . 
   
   
       9 . The composition of  claim 1 , wherein said composition comprises about 10 mg vitamin B 5 . 
   
   
       10 . The composition of  claim 1 , wherein said composition comprises about 30 mg vitamin B 6 . 
   
   
       11 . The composition of  claim 1 , wherein said composition comprises about 1000 μg vitamin B 12 . 
   
   
       12 . The composition of  claim 1 , wherein said composition comprises about 300 μg biotin. 
   
   
       13 . The composition of  claim 1 , wherein said composition comprises about 5.5 mg vitamin B 9 . 
   
   
       14 . The composition of  claim 1 , wherein said composition comprises about 70 μg selenium. 
   
   
       15 . The composition of  claim 1 , wherein said composition comprises about 20 mg zinc. 
   
   
       16 . The composition of  claim 1 , wherein said composition comprises about 100 mg vitamin C; about 60 IU vitamin E; about 3 mg vitamin B 1 ; about 2 mg vitamin B 2 ; about 20 mg vitamin B 3 ; about 10 mg vitamin B 5 ; about 30 mg vitamin B 6 ; about 1000 μg vitamin B 12 ; about 300 μg biotin; about 5.5 mg vitamin B 9 ; about 70 μg selenium; and about 20 mg zinc. 
   
   
       17 . The composition of  claim 1 , wherein said composition is substantially free of other added vitamins and minerals. 
   
   
       18 . The composition of  claim 1 , wherein said composition is administered to said patient daily. 
   
   
       19 . The composition of  claim 1 , wherein said composition is administered to said patient orally. 
   
   
       20 . The composition of  claim 1 , wherein said composition further comprises a pharmaceutically acceptable carrier. 
   
   
       21 . The composition of  claim 1 , wherein said composition is administered to a patient suffering from kidney disease. 
   
   
       22 . The composition of  claim 21 , wherein said kidney disease is end-stage renal disease. 
   
   
       23 . The composition of  claim 1 , wherein said composition is administered to a patient suffering from renal insufficiency. 
   
   
       24 . The composition of  claim 1 , wherein said composition is administered to patient undergoing dialysis therapy. 
   
   
       25 . The composition of  claim 1 , wherein said nutritional deficiencies are a result of dietary restrictions. 
   
   
       26 . The composition of  claim 1 , wherein said nutritional deficiencies are a result of a disease state. 
   
   
       27 . The composition of  claim 26 , wherein said disease state is kidney disease. 
   
   
       28 . The composition of  claim 27 , wherein said kidney disease is end-stage renal disease. 
   
   
       29 . The composition of  claim 1 , wherein said nutritional deficiencies are a result of dialysis therapy. 
   
   
       30 . The composition of  claim 26 , wherein said disease state leads to increased oxidative stress in said patient. 
   
   
       31 . The composition of  claim 26 , wherein said disease state leads to elevated cholesterol levels in said patient. 
   
   
       32 . A method for supplementing nutritional deficiencies in a patient comprising the step of administering to said patient a composition comprising about 60 mg to about 140 mg vitamin C; about 40 IU to about 80 IU vitamin E; about 1.5 mg to about 4.5 mg vitamin B 1 ; about 1 mg to about 3 mg vitamin B 2 ; about 10 mg to about 30 mg vitamin B 3 ; about 5 mg to about 15 mg vitamin B 5 ; about 18 mg to about 42 mg vitamin B 6 ; about 500 μg to about 1500 μg vitamin B 12 ; about 150 μg to about 450 μg biotin; about 3 mg to about 8 mg vitamin B g ; about 35 μg to about 105 μg selenium; and about 10 mg to about 30 mg zinc. 
   
   
       33 . A method for supplementing nutritional deficiencies in a patient comprising the step of administering to said patient a composition comprising about 80 mg to about 120 mg vitamin C; about 48 IU to about 72 IU vitamin E; about 2.4 mg to about 3.6 mg vitamin B 1 ; about 1.6 mg to about 2.4 mg vitamin B 2 ; about 16 mg to about 24 mg vitamin B 3 ; about 8 mg to about 12 mg vitamin B 5 ; about 24 mg to about 36 mg vitamin B 6 ; about 800 μg to about 1200 μg vitamin B 12 ; about 240 μg to about 360 μg biotin; about 4.4 mg to about 6.6 mg vitamin B 9 ; about 56 μg to about 84 μg selenium; and about 16 mg to about 24 mg zinc. 
   
   
       34 . A method for supplementing nutritional deficiencies in a patient comprising the step of administering to said patient a composition comprising about 90 mg to about 110 mg vitamin C; about 54 IU to about 66 IU vitamin E; about 2.7 mg to about 3.3 mg vitamin B 1 ; about 1.8 mg to about 2.2 mg vitamin B 2 ; about 18 mg to about 22 mg vitamin B 3 ; about 9 mg to about 11 mg vitamin B 5 ; about 27 mg to about 33 mg vitamin B 6 ; about 900 μg to about 1100 μg vitamin B 12 ; about 270 μg to about 330 μg biotin; about 4.95 mg to about 6.05 mg vitamin B 9 ; about 63 μg to about 77 μg selenium; and about 18 mg to about 22 mg zinc. 
   
   
       35 . The method of  claim 32 , wherein said composition comprises about 100 mg vitamin C. 
   
   
       36 . The method of  claim 32 , wherein said composition comprises about 60 IU vitamin E. 
   
   
       37 . The method of  claim 32 , wherein said composition comprises about 3 mg vitamin B 1 . 
   
   
       38 . The method of  claim 32 , wherein said composition comprises about 2 mg vitamin B 2 . 
   
   
       39 . The method of  claim 32 , wherein said composition comprises about 20 mg vitamin B 3 . 
   
   
       40 . The method of  claim 32 , wherein said composition comprises about 10 mg vitamin B 5 . 
   
   
       41 . The method of  claim 32 , wherein said composition comprises about 30 mg vitamin B 6 . 
   
   
       42 . The method of  claim 32 , wherein said composition comprises about 1000 μg vitamin B 12 . 
   
   
       43 . The method of  claim 32 , wherein said composition comprises about 300 μg biotin. 
   
   
       44 . The method of  claim 32 , wherein said composition comprises about 5.5 mg vitamin B 9 . 
   
   
       45 . The method of  claim 32 , wherein said composition comprises about 70 μg selenium. 
   
   
       46 . The method of  claim 32 , wherein said composition comprises about 20 mg zinc. 
   
   
       47 . The method of  claim 32 , wherein said composition comprises about 100 mg vitamin C; about 60 IU vitamin E; about 3 mg vitamin B 1 ; about 2 mg vitamin B 2 ; about 20 mg vitamin B 3 ; about 10 mg vitamin B 5 ; about 30 mg vitamin B 6 ; about 1000 μg vitamin B 12 ; about 300 μg biotin; about 5.5 mg vitamin B 9 ; about 70 μg selenium; and about 20 mg zinc. 
   
   
       48 . The method of  claim 32 , wherein said composition is substantially free of other added vitamins and minerals. 
   
   
       49 . The method of  claim 32 , wherein said composition is administered to said patient daily. 
   
   
       50 . The method of  claim 32 , wherein said composition is administered to said patient orally. 
   
   
       51 . The method of  claim 32 , wherein said composition further comprises a pharmaceutically acceptable carrier. 
   
   
       52 . The method of  claim 32 , wherein said composition is administered to a patient suffering from kidney disease. 
   
   
       53 . The method of  claim 52 , wherein said kidney disease is end-stage renal disease. 
   
   
       54 . The method of  claim 32 , wherein said composition is administered to a patient suffering from renal insufficiency. 
   
   
       55 . The method of  claim 32 , wherein said composition is administered to patient undergoing dialysis therapy. 
   
   
       56 . The method of  claim 32 , wherein said nutritional deficiencies are a result of dietary restrictions. 
   
   
       57 . The method of  claim 32 , wherein said nutritional deficiencies are a result of a disease state. 
   
   
       58 . The method of  claim 57 , wherein said disease state is kidney disease. 
   
   
       59 . The method of  claim 58 , wherein said kidney disease is end-stage renal disease. 
   
   
       60 . The method of  claim 32 , wherein said nutritional deficiencies are a result of dialysis therapy. 
   
   
       61 . The method of  claim 57 , wherein said disease state leads to increased oxidative stress in said patient. 
   
   
       62 . The method of  claim 57 , wherein said disease state leads to elevated cholesterol levels in said patient.

Join the waitlist — get patent alerts

Track US2010196508A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.