Antibodies for identifying and/or isolating at least one cell population

Abstract

Monoclonal antibodies, or fragments thereof, are used for isolating and/or identifying at least one cell population. The cell population can include any of the following types of cells: haematopoietic stem cells, neuronal stem cells, neuronal progenitor cells, mesenchymal stem cells and mesenchymal progenitor cells. The antibodies, or fragments thereof, bind to an antigen which is the same as that bound by an antibody which is produced by the hybridoma cell lines CUB1, CUB2, CUB3 and CUB4, which were deposited in the DSMZ under the numbers DSM ACC2569, DSM ACC2566 and DSM ACC2565, on 14 Aug. 2002, and DSM ACC2551, on 12 Jul. 2002.

1 . An antibody that selectively binds to a protein having the amino acid sequence of CUB domain-containing protein (CDCP1), or a fragment thereof. 
     
     
         2 . The antibody of  claim 1 , wherein the antibody is a monoclonal or a polyclonal antibody. 
     
     
         3 . The antibody of  claim 1 , wherein the protein having the amino acid sequence of CUB domain-containing protein (CDCP1) is glycosylated or the fragment of SEQ ID NO:1 is glycosylated. 
     
     
         4 . The antibody of  claim 1 , wherein the protein having the amino acid sequence of CUB domain-containing protein (CDCP1) is not glycosylated or the fragment of the amino acid sequence of CUB domain-containing protein (CDCP1) is not glycosylated. 
     
     
         5 . An isolated protein having the amino acid sequence of CUB domain-containing protein (CDCP1) that is glycosylated.