Pharmaceutical compositions and methods for relieving pain and treating central nervous system disorders

Abstract

Patients susceptible to or suffering from disorders, such as central nervous system disorders, which are characterized by an alteration in normal neurotransmitter release, such as dopamine release (e.g., Parkinsonism, Parkinson's Disease, Tourette's Syndrome, attention deficient disorder, or schizophrenia), are treated by administering a compound of Formulas 1 or 2, as described herein. The compounds of Formulas 1 and 2 are also useful for treating pain, and treating drug addiction, nicotine addiction, and/or obesity. The compounds can exist as individual stereoisomers, racemic mixtures, diastereomers and the like.

1 . A compound 3-methyl-7-(3-pyridinyl)-3-azabicyclo[3.3.1]non-6-ene or a pharmaceutically acceptable salt thereof. 
   
   
       2 . The dihydrochloride salt of the compound of  claim 1 . 
   
   
       3 . A pharmaceutical composition comprising 3-methyl-7-(3-pyridinyl)-3-azabicyclo[3.3.1]non-6-ene or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. 
   
   
       4 . The pharmaceutical composition of  claim 3 , comprising 3-methyl-7-(3-pyridinyl)-3-azabicyclo[3.3.1]non-6-ene dihydrochloride salt.