Aequorin-Containing Compositions and Methods of Using Same

Abstract

Compositions containing aequorin and methods for their use in preventing and/or alleviating symptoms and disorders related to calcium imbalance are provided by the present invention.

1 . A composition for preventing or alleviating a symptom or disorder associated with calcium imbalance comprising:
 (a) an effective amount of aequorin; and   (b) an acceptable carrier.   
   
   
       2 . The composition according to  claim 1  further comprising an immune boosting agent, anti-inflammatory agent, anti-oxidant agent, anti-viral agent, or a mixture thereof. 
   
   
       3 . The composition according to  claim 1 , wherein said composition is in a unit dosage form selected from the group consisting of a tablet, a capsule, a solution, a suspension, a syrup, a beverage, an oral or ophthalmic formulation and an injection. 
   
   
       4 . A method for preventing or alleviating a symptom or disorder associated with calcium imbalance comprising administering to a subject in need of such treatment an effective amount of aequorin. 
   
   
       5 . The method according to  claim 4  wherein the symptom or disorder associated with calcium imbalance is related to neuronal excitability, muscle contraction, membrane permeability, cell division, hormone secretion or bone mineralization. 
   
   
       6 . The method according to  claim 4  wherein the symptom or disorder is caused by ischemia. 
   
   
       7 . The method according to  claim 4 , wherein said effective amount of aequorin is provided in combination with an immune boosting agent, anti-inflammatory agent, anti-oxidant agent, anti-viral agent, or a mixture thereof. 
   
   
       8 . The method according to  claim 4  wherein said effective amount of aequorin is in a unit dosage form selected from the group consisting of a tablet, a capsule, a solution, a suspension, a syrup, a beverage, an oral or ophthalmic formulation and an injection.