Composition containing metal-acidic amino acid chelate accelerating absorption of metal

Abstract

Provided is a composition for accelerating absorption of metals, comprising a metal-acidic amino acid chelate as an active ingredient. The composition of the present invention has therapeutic effects on prevention and treatment of various diseases arising from a deficiency or shortage of metals, by utilization of a metal-acidic amino acid chelate that exhibits excellent effects of improving delivery and absorption of a drug into target organs, such that pharmaceutical effects of individual metals can be exerted. In particular, a pharmaceutical composition comprising a zinc-aspartate chelate increasing an intraprostatic zinc content as an active ingredient is highly effective for prevention and treatment of prostate and testicular diseases.

1 . A composition for accelerating absorption of metals, comprising a metal-acidic amino acid chelate as an active ingredient. 
   
   
       2 . The composition according to  claim 1 , wherein the amino acid is at least one selected from the group consisting of aspartate, glutamate and a mixture thereof, and the metal is one or more selected from divalent metals. 
   
   
       3 . The composition according to  claim 1 , wherein the metal is zinc and the acidic amino acid is aspartate. 
   
   
       4 . The composition according to  claim 1 , wherein the composition comprises a pharmaceutically acceptable carrier. 
   
   
       5 . The composition according to  claim 1 , wherein the composition comprises a sitologically acceptable carrier. 
   
   
       6 . The composition according to  claim 1 , wherein the composition comprises a cosmetically acceptable carrier. 
   
   
       7 . A pharmaceutical composition for prevention and treatment of a disease, comprising a zinc-aspartate chelate as an active ingredient, wherein the disease is selected from the group consisting of developmental abnormality of genital organs, abnormal production and activity of gonadal hormones, abnormal production of insulin, weakening of immune functions, recession of sexual function, anorexia, prostate disorders, thyroid hyperfunction, a decreased resistance to diseases, gustatory dysfunction, glucose metabolic abnormalities, and alopecia. 
   
   
       8 . A pharmaceutical composition for prevention and treatment of prostate and/or testicular diseases, comprising a zinc-aspartate chelate as an active ingredient. 
   
   
       9 . The composition according to  claim 8 , wherein the prostate disease is selected from the group consisting of prostatitis, enlargement of prostate (benign prostatic hyperplasia) and prostate cancer. 
   
   
       10 . A pharmaceutical preparation comprising the composition of any one of  claims 1  to  9 . 
   
   
       11 . The preparation according to  claim 10 , wherein the preparation is for oral administration. 
   
   
       12 . A pharmaceutical preparation comprising a zinc-aspartate chelate-containing composition as an active ingredient, wherein the preparation is designed to administer zinc in an amount of more than 15 mg/day. 
   
   
       13 . A pharmaceutical preparation comprising a zinc-aspartate chelate-containing composition as an active ingredient, wherein the preparation is targeted into the prostate or gonad.