Process of fabricating tissue array block, process of fabricating tissue array sheet, tissue array block, tissue array chip, system of fabricating tissue array block and system of fabricating tissue array sheet

Abstract

[Task] A process of fabricating a tissue array block; a process of fabricating a tissue array sheet; a tissue array block; a tissue array chip; a system of fabricating a tissue array block; and a system of fabricating a tissue array sheet are proposed, in which the tissue array block can be fabricated even in the case of that having a small thickness, is little affected by tissue hardness and, when having been processed into a tissue array chip, does not suffer any defect in a piece of tissue or at a site of interests, enables the collection of pieces of tissue from a dispersed area, also enables the establishment of positional relationship between the inside of a tissue piece and the inside of a tissue block, and scarcely affects the utilization of the tissue block remaining after collecting the pieces of tissue. [Solving Means] A tissue block B 1 is sliced to fabricate roll-shaped pieces of tissue t 2 . Then, the roll-shaped tissue pieces t 2 are inserted into a base block B 2 to give a tissue array block B 3 . The tissue array block B 3 is sliced into tissue array sheets S 1 , which is then mounted on a substrate to give a tissue array chip C 1 . Pieces of tissue on the tissue array chip C 1 are spirally shaped.

1 . A process of fabricating a tissue array block, comprising the steps of slicing a tissue block to obtain roll-shaped pieces of tissue and inserting the roll-shaped pieces of tissue in an axial direction into holes arrayed in a base block. 
   
   
       2 . A process of fabricating a tissue array block, comprising the steps of slicing a tissue block to obtain sheet-like pieces of tissue, coiling and rolling the sheet-like pieces of tissue to form roll-shaped pieces of tissue, and inserting the roll-shaped pieces of tissue in an axial direction into holes arrayed in a base block. 
   
   
       3 . A process of fabricating a tissue array block according to  claim 1 , further comprising the step of cutting the roll-shaped pieces of tissue to have a predetermined length, which step is taken before or after the step of inserting the roll-shaped pieces of tissue. 
   
   
       4 . A process of fabricating a tissue array sheet, comprising the step of slicing the tissue array block fabricated by the process according to  claim 1  in a direction in which the pieces of tissue inserted into the holes have a spiral shape in cross section. 
   
   
       5 . A tissue array block that retains plural pieces of tissue on a base block, wherein the pieces of tissue are roll-shaped. 
   
   
       6 . A tissue array chip having plural pieces of tissue arrayed on a substrate, wherein the pieces of tissue are roll-shaped. 
   
   
       7 . A system of fabricating a tissue array block, comprising means for slicing a tissue block to obtain roll-shaped pieces of tissue, means for cutting the roll-shaped pieces of tissue at predetermined positions, and means for and inserting the roll-shaped pieces of tissue in an axial direction into holes arrayed in a base block. 
   
   
       8 . A system of fabricating a tissue array sheet, comprising the system of fabricating a tissue array block according to  claim 7  and means for slicing the tissue array block fabricated by the system of fabricating a tissue array block in a direction in which the pieces of tissue have a spiral shape in cross section.