US2010081824A1PendingUtilityA1

Processes For the preparation of different forms of (S)-(+)-Clopidogrel besylate

Assignee: CADILA HEALTHCARE LTDPriority: Sep 5, 2005Filed: Dec 1, 2009Published: Apr 1, 2010
Est. expirySep 5, 2025(expired)· nominal 20-yr term from priority
A61P 9/10C07D 495/04
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Claims

Abstract

Improved processes for the preparation of different forms of (S)-(+)-Clopidogrel besylate, pharmaceutical compositions containing them and their use in medicine.

Claims

exact text as granted — not AI-modified
1 . A process for the preparation of amorphous form of (S)-(+)-Clopidogrel besylate comprising:
 i. treating Clopidogrel base with benzene sulfonic acid in suitable solvent(s) selected from tetrahydrofuran, methyl isobutyl ketone, or their suitable mixtures; and   ii. removing the solvent to obtain the amorphous form.

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