Method of implanting a prosthetic valve

Abstract

Methods of implanting a prosthetic valve in a body vessel are provided. A first expandable frame member is delivered to and deployed at a point of treatment in a body vessel. A second expandable frame member is delivered to the point of treatment. The second expandable frame member has an attached graft member that forms a valve adapted to permit fluid flow through the body vessel in a first direction and to substantially prevent fluid flow through the body vessel in a second, opposite direction. After deployment of the first expandable frame member, the second expandable frame member is deployed at the point of treatment such that the second frame member is positioned radially inward of the first frame member within said body vessel to form a prosthetic valve.

1 . A method of implanting a prosthetic valve in a body vessel, comprising:
 providing a first expandable frame member having unexpanded and expanded configurations;   providing a second expandable frame member having unexpanded and expanded configurations, the second expandable frame member having an attached graft member forming a valve adapted to permit fluid flow through said body vessel in a first direction and to substantially prevent fluid flow through said body vessel in a second, opposite direction;   percutaneously delivering the first frame member to a point of treatment in said body vessel;   deploying the first frame member at the point of treatment;   percutaneously delivering the second frame member with the attached graft member to the point of treatment;   after deploying the first frame member at the point of treatment, deploying the second frame member with the attached graft member at the point of treatment such that the second frame member is positioned radially inward of the first frame member within said body vessel to form said prosthetic valve.   
   
   
       2 . The method of  claim 1 , wherein at least one of the first expandable frame member and the second expandable frame member comprises a self-expandable member. 
   
   
       3 . The method of  claim 1 , wherein at least one of the first expandable frame member and the second expandable frame member requires the application of an outwardly-directed expansile force to induce expansion. 
   
   
       4 . The method of  claim 1 , wherein at least one of the first expandable frame member and the second expandable frame member comprises a tubular member. 
   
   
       5 . The method of  claim 1 , wherein at least one of the first expandable frame member and the second expandable frame member comprises a stent. 
   
   
       6 . The method of  claim 6 , wherein at least one of the first expandable frame member and the second expandable frame member comprises a wire frame member. 
   
   
       7 . The method of  claim 6 , wherein at least one of the first expandable frame member and the second expandable frame member comprises a solid tubular member. 
   
   
       8 . The method of  claim 6 , wherein at least one of the first expandable frame member and the second expandable frame member comprises a tubular member with openings therein. 
   
   
       9 . The method of  claim 1 , wherein one of the first expandable frame member and the second expandable frame member comprises a self-expandable frame member and the other of the first expandable frame member and the second expandable frame member requires the application of an outwardly-directed expansile force to induce expansion. 
   
   
       10 . The method of  claim 1 , wherein the graft member comprises a natural material. 
   
   
       11 . The method of  claim 10 , wherein the graft member comprises a bioremodellable material. 
   
   
       12 . The method of  claim 10 , wherein the graft member comprises an extracellular matrix material. 
   
   
       13 . The method of  claim 10 , wherein the graft member comprises small intestine submucosa. 
   
   
       14 . The method of  claim 1 , wherein the graft member comprises a synthetic material. 
   
   
       15 . The method of  claim 14 , wherein the graft member comprises a polymeric material. 
   
   
       16 . The method of  claim 14 , wherein the graft member comprises one of expanded polytetrafluoroethylene and polyurethane. 
   
   
       17 . The method of  claim 1 , wherein the graft member comprises a tubular member. 
   
   
       18 . The method of  claim 1 , wherein the first frame member defines a sinus portion. 
   
   
       19 . A method of implanting a prosthetic valve in a body vessel, comprising:
 providing a first expandable frame member having unexpanded and expanded configurations, the first frame member defining a sinus portion;   providing a second expandable frame member having unexpanded and expanded configurations, the second expandable frame member having an attached graft member forming a valve adapted to permit fluid flow through said body vessel in a first direction and to substantially prevent fluid flow through said body vessel in a second, opposite direction;   percutaneously delivering the first frame member to a point of treatment in said body vessel;   deploying the first frame member at the point of treatment;   percutaneously delivering the second frame member with the attached graft member to the point of treatment;   after deploying the first frame member at the point of treatment, deploying the second frame member with the attached graft member at the point of treatment such that the second frame member is positioned radially inward of the first frame member within said body vessel to form said prosthetic valve.   
   
   
       20 . A method of implanting a prosthetic valve in a body vessel, comprising:
 providing a first expandable frame member having unexpanded and expanded configurations, the first frame member having a first axial length and defining a sinus portion;   providing a second expandable frame member having unexpanded and expanded configurations, the second expandable frame member having a second axial length and an attached graft member forming a valve adapted to permit fluid flow through said body vessel in a first direction and to substantially prevent fluid flow through said body vessel in a second, opposite direction, the first axial length being greater than the second axial length;   percutaneously delivering the first frame member to a point of treatment in said body vessel;   deploying the first frame member at the point of treatment;   percutaneously delivering the second frame member with the attached graft member to the point of treatment;   after deploying the first frame member at the point of treatment, deploying the second frame member with the attached graft member at the point of treatment such that the second frame member is positioned radially inward of the first frame member within said body vessel and such that the valve is positioned substantially adjacent the sinus portion to form said prosthetic valve.