Integrated receiver for continuous analyte sensor

Abstract

A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.

1 . A system comprising:
 a continuous sensor configured for at least partial insertion into a host, wherein the continuous sensor generates continuous sensor data associated with an analyte concentration in the host;   a single point monitor external to the host, wherein the single point monitor generates at least one single point value associated with an analyte concentration of a biological sample received from the host; and   a processing unit configured to calibrate the continuous sensor data using the single point value from the single point monitor, wherein the processing unit is in data communication with the continuous sensor and configured to receive and process the continuous sensor data from the continuous sensor, and wherein the single point monitor is physically connected to the processing unit.   
     
     
         2 . The system of  claim 1 , wherein each of the continuous sensor and the single point monitor comprise a sensing membrane comprising an enzyme domain, and wherein the enzyme domain of the sensing membrane of the continuous sensor and the enzyme domain of the sensing membrane of the single point monitor are substantially the same. 
     
     
         3 . The system of  claim 1 , wherein the single point monitor is configured to receive a single use test strip. 
     
     
         4 . The system of  claim 1 , wherein the processing unit further comprises programming to control administration of a constituent to the host. 
     
     
         5 . The system of  claim 4 , wherein the programming to control administration of a constituent to the host is configured to determine at least one of an amount of insulin and a time of insulin administration. 
     
     
         6 . The system of  claim 1 , wherein the processing unit further comprises programming to calculate a rate of change of the continuous sensor data and/or directional trend of the continuous sensor data. 
     
     
         7 . The system of  claim 6 , wherein the processing unit further comprises programming to control administration of a constituent to the host based at least in part on a rate of change of the continuous sensor data and/or a directional trend of the continuous sensor data. 
     
     
         8 . The system of  claim 1 , wherein the processing unit further comprises programming to control administration of a constituent to the host based at least in part on the at least one single point value. 
     
     
         9 . The system of  claim 1 , wherein the processing unit is configured to monitor the continuous sensor data to adaptively determine a time for requesting a biological sample. 
     
     
         10 . The system of  claim 1 , further comprising a user interface associated with the processing unit and the single point monitor, wherein the processing unit is configured to prompt the user, via the user interface, to provide a biological sample to the single point monitor at predetermined intervals. 
     
     
         11 . The system of  claim 1 , further comprising a user interface associated with the processing unit and the single point monitor, wherein the processing unit is configured to prompt the user to provide a biological sample to the single point monitor based upon one or more events. 
     
     
         12 . The system of  claim 11 , wherein the one or more events comprise one or more events selected from the group consisting of meals, exercise, large excursions in analyte levels, and faulty or interrupted data readings. 
     
     
         13 . The system of  claim 1 , wherein processing unit is configured to compare the single point value with one or more acceptability parameters. 
     
     
         14 . The system of  claim 1 , further comprising a user interface associated with the processing unit and the single point monitor, wherein the user interface is configured to display the single point value from the single point monitor and the continuous sensor data from the continuous sensor on the user interface. 
     
     
         15 . The system of  claim 1 , further comprising a user interface associated with the processing unit and the single point monitor, wherein the user interface is configured to simultaneously display the single point value and a graphical representation of the continuous sensor data. 
     
     
         16 . The system of  claim 1 , further comprising a user interface associated with the processing unit and the single point monitor, wherein the user interface is configured to selectively display the single point value and the continuous sensor data responsive to user interaction. 
     
     
         17 . The system of  claim 1 , further comprising a drug delivery device, and wherein the processing unit is in data communication with the drug delivery device.