Epithelium-improving agent

Abstract

It is intended to provide an epithelium improving agent which improves the epithelial functions of various organs and, therefore, is usable in growing melanin-pigmented hair, relieving inflammatory symptoms in gingivitis and paradentitis, treating and relieving cold syndrome and bronchial asthma and, moreover, restoring sexual sensibility. An epithelium improving agent which comprises coenzyme Q10, cysteine, vitamins A, C and E and a skin extract of a rabbit inoculated with a vaccinia virus as the main components. In the case of treating gingivitis, paradentitis, cold syndrome and bronchial asthma, loratadine is further added. To an epithelium improving agent which is to be used in stimulating hair growth or restoring sexual sensibility, liquid paraffin and a hydrophilic ointment is further added to give a cream. Thus, the above problem can be solved.

1 .- 3 . (canceled) 
   
   
       14 . A method for improving epithelial function upon being applied or inhaled, comprising administering to a subject a therapeutically effective amount of an epithelium-improving agent containing coenzyme Q10, cysteine, vitamins, and an extract of inflamed skin from domestic rabbits inoculated with vaccinia virus. 
   
   
       15 . A method as claimed in  claim 14 , wherein the vitamins comprise Vitamins A, C, E or derivatives thereof. 
   
   
       16 . A method as claimed in  claim 14 , which is used to improve function for nasal cavity, paranasal sinuses, oral cavity, pharynx, tonsils, larynx, trachea, bronchi, alveoli, epithelium of genital organs, and hair. 
   
   
       17 . A method as claimed in  claim 14 , which is used to improve gingivitis or periodontitis. 
   
   
       18 . A method as claimed in  claim 14 , which is used to improve the common cold. 
   
   
       19 . A method as claimed in  claim 14 , which is used to improve bronchial asthma. 
   
   
       20 . A method as claimed in  claim 14 , which is used to improve sexual sensation. 
   
   
       21 . A method as claimed in  claim 14 , which is used for hair growth involving the growth of melanin pigment-containing black hair from areas with white hair. 
   
   
       22 . A method as claimed in  claim 14 , wherein the cysteine is L-cysteine or derivatives thereof. 
   
   
       23 . A method as claimed in  claim 15 , wherein the Vitamin A is retinole palmitate or derivatives thereof. 
   
   
       24 . A method as claimed in  claim 15 , wherein the Vitamin C is ascorbic acid or derivatives thereof. 
   
   
       25 . A method as claimed in  claim 15 , wherein the Vitamin E is tocopherol or derivatives thereof. 
   
   
       26 . A method as claimed in  claim 14 , wherein the Vitamins are a mixture of retinole palmitate or derivatives thereof, ascorbic acid or derivatives thereof and tocopherol or derivatives thereof. 
   
   
       27 . A method as claimed in  claim 14 , wherein the epithelium-improving agent comprising;
 coenzyme Q10 (0.03 to 1.2 weight parts),   L-cysteine (0.48 to 2.4 weight parts),   Vitamin A (0.06 to 0.36 weight parts),   Vitamin C (2.0 to 8.0 weight parts),   Vitamin E (0.4 to 1.6 weight parts),   extract of inflamed skin from domestic rabbit inoculated with vaccinia virus 3.6 to 14.4 units, 3 ml to 12 ml, (0.6 to 2.4 weight parts) and   liquid paraffin (4.4 to 13.2 weight parts) relative to 500 weight parts hydrophilic ointment as an epithelium-improving agent in the form of cream for improving sexual sensation and for application to hair growth.   
   
   
       28 . A method as claimed in  claim 14 , wherein the epithelium-improving agent comprising;
 coenzyme Q10 (0.03 to 1.2 weight parts),   L-cysteine (0.48 to 2.4 weight parts),   Vitamin A (0.06 to 0.36 weight parts),   Vitamin C (2.0 to 8.0 weight parts),   Vitamin E (0.4 to 1.6 weight parts),   extract of inflamed skin from domestic rabbit inoculated with vaccinia virus 3.6 to 14.4 units, 3 ml to 12 ml, (0.6 to 2.4 weight parts) and   loratadine (0.01 to 0.12 weight parts) per 500 weight parts purified water as a liquid epithelium-improving agent for application to gingival inflammation, periodontitis, and for inhalation by nebulizer to treat the common cold and bronchial asthma.