Novel Triazolo pyrimidine compounds

Abstract

The present invention relates to a pyrimidine compound (I) useful as a pharmaceutical intermediate, to a process for preparing said pyrimidine compound, to intermediates used in said process, and to the use of said pyrimidine compound in the preparation of pharmaceuticals.

1 . (canceled) 
   
   
       2 . (canceled) 
   
   
       3 . (canceled) 
   
   
       4 . (canceled) 
   
   
       5 . (canceled) 
   
   
       6 . The use of a compound of formula (I) to prepare a compound of formula (A): 
     
       
         
         
             
             
         
       
       comprising: 
       (a) reacting a compound of formula (I) with an alkali metal nitrite in the presence of a suitable acid to prepare a compound of formula (VII): 
     
     
       
         
         
             
             
         
       
       (b) coupling the compound of formula (VII) with a compound of formula (VI): 
     
     
       
         
         
             
             
         
       
       to provide a compound of formula (V): and, 
     
     
       
         
         
             
             
         
       
       (c) deprotecting a compound of formula (V) to provide the compound of formula (A). 
     
   
   
       7 . (canceled) 
   
   
       8 . (canceled) 
   
   
       9 . An intermediate compound of formula (II), (IV), (VII), (VIII), (X) or (XI) or a salt of a compound of formula (III).