Gene and methods for diagnosing neuropsychiatric disorders and treating such disorders

Abstract

A mammalian 22444 gene and gene products which are predictive of a susceptibility or predisposition to various neuropsychiatric disorders are provided. Methods of predicting an individual's susceptibility to developing or having a neuropsychiatric disorder via detection of these diagnostic markers are also provided. In addition, compositions and methods for identifying compositions for use in the treatment of neuropsychiatric disorders via these genes and gene products are described.

1 . A method for predicting the susceptibility of an individual for having or developing a neuropsychiatric disorder comprising obtaining a biological sample from the individual and screening the biological sample for the presence or absence of the mammalian 22444 gene of  claim 1  or a variant thereof wherein the absence of the nucleotide sequence or the presence of the variant is indicative of a susceptibility of the individual to have or develop a neuropsychiatric disorder. 
     
     
         2 . A method of diagnosing a neuropsychiatric disorder in an individual comprising obtaining a biological sample from the individual and analyzing the biological sample for the presence or absence of the mammalian 22444 gene of  claim 1  or a variant thereof wherein the absence of the mammalian 22444 gene or the presence of the variant is indicative of a neuropsychiatric disorder.