Cellomics system

Abstract

In labeling a cell, and separating and collecting the cell according to a degree of the labeling using a cell separator, effects on the cell is minimized and the use of the collected cell is facilitated, thereby, when labeling a cell, the cell is labeled in the state where interaction of each cell is retained. In the labeling, a specific labeling material present on a surface of a target cell is taken in the cell via a transporter, and the cell is dispersed one by one to separate the same with a cell separator. Immediately after the separation, the cell is put in a solution not containing the specific labeling substance to remove the specific labeling substance taken in the cell. This series of steps is continuously conducted with a cell separation chip.

1 . A high speed trace quantity reactor comprising: a means for transferring droplets each containing different reaction precursors respectively to collide to one another; and a detecting means for tracking reaction of the collided droplets. 
     
     
         2 . A high speed trace quantity reactor comprising: a means for transferring droplets each containing different reaction precursors respectively to collide to one another; a means for stirring the collided droplets; and a detecting means for tracking reaction of the collided droplets. 
     
     
         3 . A method of trace quantity reaction comprising the steps of:
 dissolving a plurality of reaction precursors targeted to be reacted, in respective different droplets;   putting each of the droplets in different positions on a substrate; and   making each of the droplets collide to one another on the substrate to cause reactions.   
     
     
         4 . A method of trace quantity reaction comprising the steps of:
 putting each of a droplet with a cell inserted therein and a droplet including a heterologous cell active substance in different positions on a substrate; and   making each of the droplets collide to one another on the substrate to observe effects on the cell.