US2009317278A1PendingUtilityA1

Composite artificial bone

Assignee: JAPAN SCIENCE & TECH AGENCYPriority: Aug 31, 2006Filed: Aug 28, 2007Published: Dec 24, 2009
Est. expiryAug 31, 2026(~0.1 yrs left)· nominal 20-yr term from priority
Inventors:Tadashi Kokubo
A61F 2002/30261A61F 2250/0015A61L 27/06A61F 2/4465A61F 2002/30787A61F 2002/30892A61F 2002/30153A61F 2/28A61F 2002/30957A61F 2250/0023A61F 2002/30133A61F 2230/0082A61F 2/447A61F 2002/30006A61F 2230/0015A61F 2310/00023A61F 2002/30156A61F 2002/30593A61F 2230/0019A61F 2002/30011A61F 2/4455A61L 2430/02A61L 27/56A61F 2230/0023A61F 2002/30843A61F 2002/30968
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Claims

Abstract

An artificial bone which is easy to bond to a living bone and has a mechanical property approximate to that of a living bone is disclosed. The artificial bone comprises: a dense part made of titanium or a titanium alloy, in the shape of a frame that is approximate to a part of an outer face of a living bone, having a density of 95% or more; and a porous part made of sintered particles of titanium or a titanium alloy having the same or different composition as the titanium alloy for the dense part, in the shape approximate to the remaining part of the living bone, having a porosity of 40% or more, the dense part and the particles of the porous part being sintered to each other at an interface between the dense part and the porous part.

Claims

exact text as granted — not AI-modified
1 - 6 . (canceled) 
   
   
       7 . A method of producing an artificial bone, the method comprising the steps of:
 preparing a die having an inner face that is complementary with a living bone;   placing a shaped body (a) of titanium or a titanium alloy powder not containing a pore forming agent, having a frame shape that is approximate with a part of an outer face of the living bone, in the die ; charging the remaining space of the die with a mixture containing titanium or a titanium alloy powder and a pore forming agent ; pressure-molding the mixture, to obtain a shaped body (b) and combine the shaped body (b) with the shaped body (a) ; and calcining the combined body.   
   
   
       8 . The method according to  claim 7 , wherein the part of the outer face of the living bone is a part including a corner, an edge line or a surface of the living bone. 
   
   
       9 . The method according to  claim 8 , wherein the shaped body (a) has a sharp projection on one end face. 
   
   
       10 . The method according to  claim 7 , wherein either one or both of the shaped body (a) and the shaped body (b) contain an organic binder. 
   
   
       11 . The method according to  claim 7 , wherein the organic binder is composed of 0 to 50 vol % of polyacetal, 0 to 50 vol % of polypropylene and 50 to 70 vol % of waxes. 
   
   
       12 . The method according to  claim 7 , wherein the pressure molding is conducted at a pressure of 20 to 100 MPa. 
   
   
       13 . The method according to  claim 7 , wherein the pore forming agent contained in the mixture is ammonium hydrogen carbonate. 
   
   
       14 . The method according to  claim 13 , wherein the pore forming agent contained in the mixture has a particle size adjusted to 500 to 1500 μm by means of a sieve.

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