US2009286313A1PendingUtilityA1

Non-steroidal anti-inflammatory drug activated gene with anti-tumorigenic properties

Assignee: SERVICEPriority: Sep 8, 2000Filed: May 11, 2009Published: Nov 19, 2009
Est. expirySep 8, 2020(expired)· nominal 20-yr term from priority
C07K 14/495C07K 14/4747G01N 33/5082A01K 2217/05A61P 35/00G01N 2500/10
55
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Claims

Abstract

The present invention provides methods and compositions for drug screens to identify and characterize agents that are agonistic or antagonistic to activation of the promoter region of the NAG-1 gene. Activation of the NAG-1 gene is associated with the apoptotic elimination of cancer cells both in vitro and in vivo. The invention also provides novel promoter region sequences of the NAG-1 gene.

Claims

exact text as granted — not AI-modified
1 - 14 . (canceled) 
     
     
         15 . An isolated or purified antibody reactive with a polypeptide encoded by a nucleic acid sequence comprising SEQ ID NO: 2. 
     
     
         16 . A composition comprising the isolated or purified antibody of  claim 15 . 
     
     
         17 . A host cell comprising the isolated or purified antibody of  claim 15 .

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