US2009264622A1PendingUtilityA1

Rhesus monkey Nur77

47
Individually held — no corporate assignee on recordPriority: Mar 16, 2005Filed: Mar 27, 2009Published: Oct 22, 2009
Est. expiryMar 16, 2025(expired)· nominal 20-yr term from priority
Inventors:Carlo J. GamboneAzriel Schmidt
C07K 14/72C07K 14/70567G01N 33/6875G01N 2500/00G01N 33/566C07K 16/2857
47
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The Macaca mulatta (rhesus monkey) Nur77 (rhNur77) nuclear receptor and the nucleic acid encoding the rhNur77 nuclear receptor are described. Further described are methods for identifying analytes that modulate expression or activity of the rhNur77 nuclear receptor. Analytes that affect Nur77 expression or activity may be used to treat or inhibit inflammatory diseases, for example, osteoarthritis and various bone, neurological, and prostrate disorders. The rhNur77 may also be used to treat various cancers, for example, prostate, ovarian, colon, lung, and gastric cancer.

Claims

exact text as granted — not AI-modified
1 . (canceled) 
     
     
         2 . (canceled) 
     
     
         3 . An isolated rhesus monkey Nur77 polypeptide comprising amino acids having the sequence set forth in SEQ ID NO: 2 or a fragment thereof. 
     
     
         4 .- 17 . (canceled) 
     
     
         18 . The isolated rhesus monkey Nur77 polypeptide of  claim 1 , wherein the polypeptide comprises amino acids 332 to 566 of SEQ ID NO: 2. 
     
     
         19 . The isolated rhesus monkey Nur77 polypeptide of  claim 1 , wherein the polypeptide comprises amino acids 265 to 332 of SEQ ID NO: 2. 
     
     
         20 . The isolated rhesus monkey Nur77 polypeptide of  claim 1 , wherein the polypeptide comprises amino acids 332 to 598 of SEQ ID NO: 2. 
     
     
         21 . The isolated rhesus monkey Nur77 polypeptide of  claim 1 , wherein amino acid 479 of SEQ ID NO: 2 is a leucine.

Join the waitlist — get patent alerts

Track US2009264622A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.