Methods of treating central nervous system disorders with a low dose combination of escitalopram and bupropion

Abstract

The present invention relates to a method of treating a central nervous system disorder, such as a mood disorder (e.g., major depressive disorder) or an anxiety disorder (e.g., general anxiety disorder, social anxiety disorder, post traumatic stress disorder, and panic disorder) with a low dose combination of escitalopram and bupropion.

1 - 10 . (canceled) 
   
   
       11 . A method for treating sexual dysfunction in a patient suffering from sexual dysfunction due to treatment with an antidepressant other than a combination of escitalopram or a pharmaceutically acceptable salt thereof and bupropion or a pharmaceutically acceptable salt thereof, comprising:
 (a) discontinuing treatment with the antidepressant; and   (b) administering daily to the patient an effective amount of bupropion or a pharmaceutically acceptable salt thereof in an amount up to about 225 mg, and an effective amount of escitalopram or a pharmaceutically acceptable salt thereof in an amount up to about 20 mg.   
   
   
       12 . The method of  claim 11 , wherein the sexual dysfunction is ejaculation disorder. 
   
   
       13 . The method of  claim 11 , wherein the sexual dysfunction is anorgasmia. 
   
   
       14 . The method of  claim 11 , wherein the sexual dysfunction is decreased libido. 
   
   
       15 . (canceled)