Dietary supplement energy-providing to skeletal muscles and protecting the cardio vascular tract

Abstract

Dietary supplements—providing energy and strengthening skeletal muscles and facilitating skeletal muscles ability to sustain prolonged periods of physical activity—containing propionyl-L-carnitine or one of its salts, coenzyme Q10, nicotinamide, riboflavin, pantothenic acid and optionally other components such as amino acids and creatines.

1 . A dietary supplement comprising as active ingredients a combination of admixed or separately packaged:
 a) propionyl L-carnitine or a pharmacologically acceptable salt thereof;   b) coenzyme Q 10 ;   c) riboflavin; and   d) pantothenic acid.   
   
   
       2 . The dietary supplement of  claim 1 , wherein component (a) further comprises a “carnitine” selected from the group consisting of L-carnitine, acetyl L-carnitine, valeryl L-carnitine, isovaleryl L-carnitine and butyryl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof. 
   
   
       3 . The dietary supplement of  claim 1  wherein the pharmacologically acceptable salt is selected from the group consisting of: chloride; bromide; iodide; aspartate, acid aspartate; citrate, acid citrate; phosphate, acid phosphate; fumarate, acid fumarate; glycerophosphate; glucose phosphate; lactate; maleate, acid maleate; mucate; orotate; oxalate; acid oxalate; sulphate, acid sulphate; tartrate; trichloroacetate; trifluoroacetate and methane sulphonate. 
   
   
       4 . The dietary supplement of  claim 1 , which further comprises at least one of the following components:
 f) an amino acid selected from the group consisting of valine, leucine, isoleucine or mixtures thereof;   g) a creative selected from the group consisting of creatine and phosphocreatine or mixtures thereof.   
   
   
       5 . The dietary supplement of  claim 1  wherein the weight ratio (a):(b):(c):(d) ranges from 10:0.04:0.08:0.4 to 1:4:4:20. 
   
   
       6 . The dietary supplement of  claim 5  wherein the weight ratio (a):(b):(c):(d) ranges from 10:2:2:2 to 1:1:1:5. 
   
   
       7 . The dietary supplement of anyone of the preceding claims in the form of tablets, lozenges, pills, capsules and granulates. 
   
   
       8 . The dietary supplement of  claim 7  in unit dosage form comprising:
 propionyl L-carnitine from 50 mg to 2,000 mg   coenzyme Q 10  from 5 mg to 200 mg   riboflavin from 5 mg to 200 mg   pantothenic acid from 10 mg to 1,000 mg.   
   
   
       9 . A method of facilitating skeletal muscles ability to sustain prolonged periods of intense physical activity comprising administering a dietary supplement consisting of as active ingredients:
 (a) propionyl L-carnitine or a pharmacologically acceptable salt thereof;   (b) coenzyme Q 10 ;   (c) riboflavin; and   (d) pantothenic acid;   
     wherein the ingredients are administered admixed together or separately. 
   
   
       10 . The method of  claim 9 , wherein component (a) further comprises a carnitine selected from the group consisting of L-carnitine, acetyl-L-carnitine, valeryl-L-carnitine, isovaleryl-L-carnitine and butyryl-L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof. 
   
   
       11 . The method of  claim 9  wherein the pharmacologically acceptable salt is selected from the group consisting of chloride, bromide, iodide, aspartate, acid aspartate, citrate, acid citrate, phosphate, acid phosphate, fumarate, acid fumarate, glycerophosphate, glucose phosphate, lactate, maleate, acid maleate, mucate, orotate, oxalate, acid oxalate, sulphate acid sulphate, tartrate, trichloroacetate, trifluoroacetate and methane sulphonate. 
   
   
       12 . The method of  claim 9  in which the dietary supplement further comprises at least one of the following components:
 (f) an amino acid selected from the group consisting of valine, leucine and isoleucine or mixtures thereof;   (g) a creatine selected from the group consisting of creatine and phosphocreatine or mixtures thereof.   
   
   
       13 . The method of  claim 9  wherein the weight ratio (a):(b):(c):(d) ranges from 10:0.04:0.08:0.4 to 1:4:4:20. 
   
   
       14 . The method of  claim 13  wherein the weight ratio (a):(b):(c):(d) ranges from 10:2:2:2 to 1:1:1:5. 
   
   
       15 . The method of  claim 9  wherein the dietary supplement is in the form of tablets, lozenges, pills, capsules or granulates. 
   
   
       16 . The method of  claim 15  wherein the composition is in a unit dosage form comprising:
 propionyl L-carnitine from 50 mg to 2,000 mg   coenzyme Q 10  from 5 mg to 200 mg   riboflavin from 5 mg to 200 mg   pantothenic acid from 10 mg to 1,000 mg.   
   
   
       17 . A method of providing energy and strengthening skeletal muscle comprising administering a dietary supplement consisting of as active ingredients:
 (a) propionyl L-carnitine or a pharmacologically acceptable salt thereof;   (b) coenzyme Q 10 ;   (c) riboflavin; and   (d) pantothenic acid;   
     wherein the ingredients are administered admixed together or separately. 
   
   
       18 . The method of  claim 17 , wherein component (a) further comprises a carnitine selected from the group consisting of L-carnitine, acetyl-L-carnitine, valeryl-L-carnitine isovaleryl-L-carnitine and butyryl-L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof. 
   
   
       19 . The method of  claim 17  wherein the pharmacologically acceptable salt is selected from the group consisting of chloride, bromide, iodide, aspartate, acid aspartate, citrate, acid citrate, phosphate, acid phosphate, fumarate, acid fumarate, glycerophosphate, glucose phosphate, lactate, maleate, acid maleate, mucate, orotate, oxalate, acid oxalate, sulphate, acid sulphate, tartrate, trichloroacetate, trifluoroacetate and methane sulphonate. 
   
   
       20 . The method of  claim 17  in which the dietary supplement further comprises at least one of the following components:
 (f) an amino acid selected from the group consisting of valine, leucine and isoleucine or mixtures thereof;   (g) a creatine selected from the group consisting of creatine and phosphocreatine or mixtures thereof.   
   
   
       21 . The method of  claim 17  wherein the weight ratio (a):(b):(c):(d) ranges from 10:0.04:0.08:0.4 to 1:4:4:20. 
   
   
       22 . The method of  claim 21  wherein the weight ratio (a):(b):(c):(d) ranges from 10:2:2:2 to 1:1:1:5. 
   
   
       23 . The method of  claim 17  wherein the dietary supplement is in the form of tablets, lozenges, pills, capsules or granulates. 
   
   
       24 . The method of  claim 23  wherein the composition is in a unit dosage form comprising:
 (a) propionyl L-carnitine or a pharmacologically acceptable salt thereof;   (b) coenzyme Q 10 ;   (c) riboflavin; and   (d) pantothenic acid.