Blood irradiatiion system, associated devices and methods for irradiating blood

Abstract

Embodiments of the present application are directed to devices, systems and methods for irradiating fluids (e.g., blood) with ultraviolet light, and corresponding related components, systems and methods. In some embodiments of the invention, an ultraviolet blood irradiation (UBI) system is provided and may include an ultraviolet UV source providing a predetermined wavelength of radiation to provide a detrimental effect to virus and/or bacteria, an exposure chamber for exposing a predetermined volume of blood to radiation, a conduit between the UV source and the exposure chamber, a pump for pumping blood between a first location and a second location and a shutter assembly provided between the UV source and the exposure chamber providing time-metered irradiation of the blood in the chamber.

1 .- 31 . (canceled) 
   
   
       32 . A method for irradiating blood comprising flowing a predetermined volume of blood through the exposure chamber and alternately exposing the flow of blood to UV radiation via a moving shutter, such that the flow of blood is exposed to the radiation according to a predetermined timing. 
   
   
       33 . An administration set for collecting a predetermined volume of blood from a patient comprising:
 a collection vessel having a predetermined pressure below atmospheric;   a first needle for inserting into the collection vessel;   a reservoir bag capable of performing as a conduit under atmospheric pressure and performing as a reservoir at or above atmospheric pressure; and   a second needle for insertion into a patient.   
   
   
       34 . The administration set according to  claim 33 , wherein the reservoir bag comprises a container having a tube, and wherein the tube includes a first port provided in a first position for transporting blood to or from the bag, a second port having an associated valve, the second port being located at a second position slightly higher vertically than the first position, and a third port provided in a third position higher vertically than the first position and the second position. 
   
   
       35 . The administration set according to  claim 34 , wherein walls of the container comprise a flexible material, and wherein the flexible material operates as the valve for the second port. 
   
   
       36 . The administration set according to  claim 34 , wherein the valve comprises a flap of flexible material provided on or adjacent the second port. 
   
   
       37 . The administration set according to  claim 34 , wherein the valve comprises a ball-in-cage valve. 
   
   
       38 . The administration set according to  claim 33 , wherein the administration set is disposable. 
   
   
       39 . The administration set according to  claim 33 , further comprising an exposure chamber. 
   
   
       40 . The administration set according to  claim 33 , further comprising at least one of a clamp, a drip tube, a stopcock. 
   
   
       41 . The administration set according to  claim 33 , wherein a portion of the tubing comprises silicon tubing. 
   
   
       42 . A container for passing and/or containing blood comprising:
 a container; and   a tube including a first port provided in a first position for transporting blood to or from the bag, a second port having an associated valve, the second port being located at a second position slightly higher vertically than the first position, and a third port provided in a third position higher vertically than the first position and the second position, wherein
 the valve closes upon application of a pressure to the first and/or third ports which is lower than atmospheric, and 
 the valve opens upon application of a pressure to the first and/or third ports of atmospheric or greater. 
   
   
   
       43 . The container according to  claim 42 , wherein walls of the container comprise a flexible material, and wherein the flexible material operates as the valve for the second port. 
   
   
       44 . The container according to  claim 42 , wherein the valve comprises a flap of flexible material provided on or adjacent the second port. 
   
   
       45 . The container according to  claim 42 , wherein the valve comprises a ball-in-cage valve.