US2009176810A1PendingUtilityA1

Composition for skin external application containing gallocatechin gallate for moisturizing effect on the skin

Assignee: AMOREPACIFIC CORPPriority: Sep 16, 2005Filed: Sep 8, 2006Published: Jul 9, 2009
Est. expirySep 16, 2025(expired)· nominal 20-yr term from priority
A61Q 19/007A61P 17/00A61K 8/498A61Q 19/00A61K 8/49
64
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Claims

Abstract

The present invention relates to a composition for external skin application having a skin-moisturizing effect, which comprises gallocatechin gallate as an active ingredient. More particularly, the composition for external skin application comprises gallocatechin gallate as an active ingredient to activate peroxisome proliferator activated receptor isoform alpha (PPAR-α), to stimulate expression of filaggrin and involucrin that are skin-moisturizing factors, and thus to provide excellent anti-drying and skin-moisturizing effects. More particularly, the composition for external skin application may further comprise theobromine and quercetin in addition to gallocatechin gallate to maximize such effects.

Claims

exact text as granted — not AI-modified
1 - 9 . (canceled) 
   
   
       10 . A composition for external skin application having a skin moisturizing effect, which comprises gallocatechin gallate as an active ingredient. 
   
   
       11 . The composition for external skin application according to  claim 10 , which further comprises theobromine and quercetin as active ingredients. 
   
   
       12 . The composition for external skin application according to  claim 11 , wherein each active ingredient is used in the following molar concentration: at least 0.4 moles of theobromine and at least 0.4 moles of quercetin in combination with 0.7 moles or less of gallocatechin gallate (GCG). 
   
   
       13 . The composition for external skin application according to  claim 11 , wherein each active ingredient is used in the following molar concentration: at least 0.3 moles of theobromine and at least 0.3 moles of quercetin in combination with 0.7˜1.4 moles or less of gallocatechin gallate (GCG). 
   
   
       14 . The composition for external skin application according to  claim 11 , wherein each active ingredient is used in the following molar concentration: at least 0.2 moles of theobromine and at least 0.2 moles of quercetin in combination with 1.4 moles or more of gallocatechin gallate (GCG). 
   
   
       15 . The composition for external skin application according to  claim 10 , wherein each active ingredient is used in an amount of 0.00130.0 wt % based on the total weight of the composition. 
   
   
       16 . The composition for external skin application according to  claim 10 , which activates PPAR-α. 
   
   
       17 . The composition for external skin application according to  claim 10 , which stimulates expression of filaggrin on the skin. 
   
   
       18 . The composition for external skin application according to  claim 10 , which stimulates expression of involucrin on the skin.

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