US2009162915A1PendingUtilityA1

Peptidylarginine Deiminase 6

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Assignee: ORGANON NVPriority: May 3, 2001Filed: Oct 14, 2008Published: Jun 25, 2009
Est. expiryMay 3, 2021(expired)· nominal 20-yr term from priority
Inventors:Jan Albert GossenPaul Van Den Boogaart
C12N 9/78G01N 2500/00C12Q 1/34
54
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Claims

Abstract

A nucleotide acid sequence is provided encoding a peptidylarginine deiminase 6. The gene is found to be expressed in gonads only and may be used as target for male and female contraception. Its encoded protein can be used to screen for small molecular weight modulators of the enzyme activity.

Claims

exact text as granted — not AI-modified
1 - 11 . (canceled) 
     
     
         12 . An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:3. 
     
     
         13 . The isolated polypeptide according to  claim 12 , wherein the polypeptide is encoded by nucleotides 20-2077 of SEQ ID NO:4. 
     
     
         14 . An isolated polypeptide having at least 95% sequence identity with SEQ ID NO:3.

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