US2009157171A1PendingUtilityA1

Treatment indications informed by a priori implant information

Assignee: SEARETE LLCPriority: Dec 18, 2007Filed: Dec 21, 2007Published: Jun 18, 2009
Est. expiryDec 18, 2027(~1.4 yrs left)· nominal 20-yr term from priority
G16H 70/60G16H 20/17A61M 2039/248A61B 5/145A61M 2205/3592A61M 2039/2413A61M 2005/1726A61M 2205/3561A61M 39/24A61M 31/00A61M 5/14276A61M 2205/04A61M 2039/242
65
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Claims

Abstract

Systems and methods are described for implementing or deploying therapeutic administration systems for obtaining a priori implant information and signaling a decision whether to initiate implant-site-targeting treatment partly based on the a priori implant information and partly based on one or more other clot-indicative determinants; or obtaining a flow-change-indicative measurement and signaling a decision whether to administer one or more clot-reducing agents at least partly based on the flow-change-indicative measurement; or obtaining one or more indications of a lactic material in a vicinity of one or more body lumens and accelerating a decrease in a local concentration of the lytic material in the vicinity of the one or more body lumens by causing one or more elements to extract at least a portion of the lytic material in the vicinity of the one or more body lumens in response to the one or more indications of the lytic material in the vicinity of the one or more body lumens; or one or more capture components configured to accelerate a decrease in a local concentration of one or more therapeutic structures along a downstream portion of a vasculature and one or more dispensation components configured to release the one or more therapeutic structures into an upstream portion of the vasculature.

Claims

exact text as granted — not AI-modified
1 - 190 . (canceled) 
   
   
       191 . A therapeutic administration system comprising:
 a processor;   one or more instructions operable by the processor to obtain one or more indications of a lytic material in a vicinity of one or more body lumens; and   one or more instructions operable by the processor to cause an acceleration of a decrease in a local concentration of the lytic material in the vicinity of the one or more body lumens by causing one or more elements to extract at least a portion of the lytic material in the vicinity of the one or more body lumens in response to the one or more indications of the lytic material in the vicinity of the one or more body lumens.   
   
   
       192 - 194 . (canceled) 
   
   
       195 . The therapeutic administration system of  claim 191  in which the one or more instructions operable by the processor to cause the acceleration of the decrease in the local concentration of the lytic material in the vicinity of the one or more body lumens comprises:
 one or more instructions operable by the processor to cause the acceleration of the portion of the lytic material to be drawn into an artificial vessel.   
   
   
       196 - 226 . (canceled) 
   
   
       227 . The therapeutic administration system of  claim 191  in which the circuitry for obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 one or more instructions operable by the processor to cause at least a statin to be dispensed as the lytic material;   one or more instructions operable by the processor to obtain a concentration-indicative scalar of the one or more indications of the lytic material;   one or more instructions operable by the processor to cause a dispensation the lytic material into an upstream portion of the one or more body lumens;   one or more instructions operable by the processor to cause the lytic material to perfuse one or more organs in the vicinity of the one or more body lumens;   one or more instructions operable by the processor to signal at least one of the one or more indications of the lytic material via a wireless signal;   one or more instructions operable by the processor to detect a marker material indicative of the lytic material in the vicinity of the one or more body lumens;   one or more instructions operable by the processor to cause the lytic material to be urged into the one or more body lumens; and   one or more instructions operable by the processor to cause an acceleration of a dispensation of the lytic material transluminally into the one or more body lumens as a programmed response to one or more pathology-indicative signals.   
   
   
       228 - 268 . (canceled) 
   
   
       269 . A therapeutic administration method comprising:
 obtaining one or more indications of a lytic material in a vicinity of one or more body lumens; and   accelerating a decrease in a local concentration of the lytic material in the vicinity of the one or more body lumens by causing one or more elements to extract at least a portion of the lytic material in the vicinity of the one or more body lumens in response to the one or more indications of the lytic material in the vicinity of the one or more body lumens.   
   
   
       270 . The therapeutic administration method of  claim 269  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 causing at least a statin to be dispensed as the lytic material.   
   
   
       271 . The therapeutic administration method of  claim 269  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 obtaining a concentration-indicative scalar of the one or more indications of the lytic material.   
   
   
       272 . The therapeutic administration method of  claim 269  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 dispensing the lytic material into an upstream portion of the one or more body lumens.   
   
   
       273 . The therapeutic administration method of  claim 269  in which the accelerating a decrease in a local concentration of the lytic material in the vicinity of the one or more body lumens by causing one or more elements to extract at least a portion of the lytic material in the vicinity of the one or more body lumens in response to the one or more indications of the lytic material in the vicinity of the one or more body lumens comprises:
 causing the portion of the lytic material to be drawn into an artificial vessel.   
   
   
       274 . The therapeutic administration method of  claim 269  in which the accelerating a decrease in a local concentration of the lytic material in the vicinity of the one or more body lumens by causing one or more elements to extract at least a portion of the lytic material in the vicinity of the one or more body lumens in response to the one or more indications of the lytic material in the vicinity of the one or more body lumens comprises:
 reversing a flow direction of at least some of the lytic material.   
   
   
       275 . The therapeutic administration method of  claim 269  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 permitting the lytic material to perfuse one or more organs in the vicinity of the one or more body lumens.   
   
   
       276 . The therapeutic administration method of  claim 269  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 signaling at least one of the one or more indications of the lytic material via a wireless signal.   
   
   
       277 . The therapeutic administration method of  claim 269  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 detecting a marker material indicative of the lytic material in the vicinity of the one or more body lumens.   
   
   
       278 . The therapeutic administration method of  claim 269  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 causing the lytic material to be urged into the one or more body lumens.   
   
   
       279 . The therapeutic administration method of  claim 269  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 accelerating a dispensation of the lytic material transluminally into the one or more body lumens as a programmed response to one or more pathology-indicative signals.   
   
   
       280 . The therapeutic administration method of  claim 269  in which the accelerating a decrease in a local concentration of the lytic material in the vicinity of the one or more body lumens by causing one or more elements to extract at least a portion of the lytic material in the vicinity of the one or more body lumens in response to the one or more indications of the lytic material in the vicinity of the one or more body lumens comprises:
 causing the lytic material to be exposed to a lytic-material-absorbent element.   
   
   
       281 . The therapeutic administration method of  claim 269  in which the accelerating a decrease in a local concentration of the lytic material in the vicinity of the one or more body lumens by causing one or more elements to extract at least a portion of the lytic material in the vicinity of the one or more body lumens in response to the one or more indications of the lytic material in the vicinity of the one or more body lumens comprises:
 causing the portion of the lytic material to be chemically deactivated.   
   
   
       282 . The therapeutic administration method of  claim 279  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 causing at least a statin to be dispensed as the lytic material.   
   
   
       283 . The therapeutic administration method of  claim 274  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 obtaining a concentration-indicative scalar of the one or more indications of the lytic material.   
   
   
       284 . The therapeutic administration method of  claim 277  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 dispensing the lytic material into an upstream portion of the one or more body lumens.   
   
   
       285 . The therapeutic administration method of  claim 275  in which the accelerating a decrease in a local concentration of the lytic material in the vicinity of the one or more body lumens by causing one or more elements to extract at least a portion of the lytic material in the vicinity of the one or more body lumens in response to the one or more indications of the lytic material in the vicinity of the one or more body lumens comprises:
 causing the portion of the lytic material to be drawn into an artificial vessel.   
   
   
       286 . The therapeutic administration method of  claim 276  in which the accelerating a decrease in a local concentration of the lytic material in the vicinity of the one or more body lumens by causing one or more elements to extract at least a portion of the lytic material in the vicinity of the one or more body lumens in response to the one or more indications of the lytic material in the vicinity of the one or more body lumens comprises:
 reversing a flow direction of at least some of the lytic material.   
   
   
       287 . The therapeutic administration method of  claim 278  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 permitting the lytic material to perfuse one or more organs in the vicinity of the one or more body lumens.   
   
   
       288 . The therapeutic administration method of  claim 277  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 signaling at least one of the one or more indications of the lytic material via a wireless signal.   
   
   
       289 . The therapeutic administration method of  claim 281  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 detecting a marker material indicative of the lytic material in the vicinity of the one or more body lumens.   
   
   
       290 . The therapeutic administration method of  claim 279  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 causing the lytic material to be urged into the one or more body lumens.   
   
   
       291 . The therapeutic administration method of  claim 280  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 accelerating a dispensation of the lytic material transluminally into the one or more body lumens as a programmed response to one or more pathology-indicative signals.   
   
   
       292 . The therapeutic administration method of  claim 269  in which the obtaining one or more indications of a lytic material in a vicinity of one or more body lumens comprises:
 causing at least a statin to be dispensed as the lytic material;   obtaining a concentration-indicative scalar of the one or more indications of the lytic material;   dispensing the lytic material into an upstream portion of the one or more body lumens;   permitting the lytic material to perfuse one or more organs in the vicinity of the one or more body lumens;   signaling at least one of the one or more indications of the lytic material via a wireless signal;   detecting a marker material indicative of the lytic material in the vicinity of the one or more body lumens;   causing the lytic material to be urged into the one or more body lumens; and   accelerating a dispensation of the lytic material transluminally into the one or more body lumens as a programmed response to one or more pathology-indicative signals.   
   
   
       293 - 322 . (canceled)

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