US2009118518A1PendingUtilityA1

Fluvastatin sodium crystal forms, processes for preparing them, compositions containing them and methods of using them

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Assignee: TEVA PHARMAPriority: Jun 18, 2003Filed: Apr 30, 2008Published: May 7, 2009
Est. expiryJun 18, 2023(expired)· nominal 20-yr term from priority
Inventors:Revital Lifshitz-LironTamas KoltaiJudith AronhimeNurit PerlmanSharon Avhar-Maydan
A61P 3/06A61P 9/04A61P 9/10A61P 43/00C07D 209/24C07D 209/12C07B 2200/13A61K 31/404A61K 31/405
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Claims

Abstract

Provided are crystalline forms of fluvastatin sodium and processes for their preparation.

Claims

exact text as granted — not AI-modified
1 . Fluvastatin sodium (Form LXVI) having an PXRD pattern with characteristic peaks at 3.6, 10.8, 17.8, 18.3 and 21.6±0.2 degrees two-theta 
     
     
         2 . The fluvastatin sodium of  claim 1 , further characterized by peaks at 7.2, 12.2, 14.4 and 25.5±0.2 degrees two-theta. 
     
     
         3 . The fluvastatin sodium of  claim 1 , further characterized by an XRD pattern as depicted in  FIG. 81 . 
     
     
         4 . A process for preparing crystalline fluvastatin of  claim 1  comprising heating a solution of fluvastatin sodium in water and cooling the solution to precipitate the crystalline form.

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