US2009054302A1PendingUtilityA1

Methods and Preparations For Curing Clinically Ill Patients

Assignee: NOVO NORDISK ASPriority: May 5, 2000Filed: Aug 22, 2008Published: Feb 26, 2009
Est. expiryMay 5, 2020(expired)· nominal 20-yr term from priority
A61P 3/08A61P 43/00A61P 7/06A61P 9/00A61P 39/02A61P 41/00A61P 29/00A61P 31/00A61P 3/10A61P 25/02A61P 25/00A61P 31/04A61P 3/00A61P 1/16A61P 17/02A61K 38/28A61P 11/00A61P 1/00A61P 13/12A61P 21/00
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Claims

Abstract

This invention relates to a life saving medicament for critically ill patients and a method of treatment. The composition is a pharmaceutically effective amount of a blood glucose regulator which is used to control the blood glucose level.

Claims

exact text as granted — not AI-modified
1 . A method of treating a patient suffering from or at risk of CIPNP, multiple organ failure, need for mechanical ventilatory support, renal replacement therapy, disturbed kidney function parameters, hyperbilirubinemia, blood stream infections, inflammations and/or inflammatory responses, need for antibiotics, red cell transfusion, stress induced hyperglycaemia, risk of repetitive positive EMGs, cholestasis, or a condition of insulin resistance leading to hyperinsulinimea in combination with hyperglycaemia, comprising treating such a patient with a blood glucose regulator. 
   
   
       2 . The method of  claim 1 , wherein the blood glucose regulator is insulin, active insulin derivatives, insulin analogues, compounds that stimulate signal transduction mediated by an insulin receptor type tyrosine kinase in a cell, protein-tyrosine phosphatases (PTP's) or other biologically active substances having insulin releasing action. 
   
   
       3 . The method of  claim 2 , wherein the blood glucose regulator is a blood glucose regulator which is not to be administered orally. 
   
   
       4 . The method of  claim 2 , wherein the blood glucose regulator is administered to maintain blood glucose levels within a range between 60-130 mg/dL. 
   
   
       5 . The method of  claim 2 , wherein the blood glucose level is maintained between 80-110 mg/dL. 
   
   
       6 . The method of  claim 2 , wherein the blood glucose level is maintained for 8 hours or more. 
   
   
       7 . The method of  claim 6 , wherein blood glucose level is maintained for 24 hours or more. 
   
   
       8 . The method of  claim 7 , wherein blood glucose level is maintained for 4 days or more. 
   
   
       9 . The method of  claim 1 , wherein the patient is a mammal. 
   
   
       10 . The method of  claim 9 , wherein the patient is a human. 
   
   
       11 . The method of  claim 10 , wherein the patient is non-diabetic.

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