US2009035837A1PendingUtilityA1

Virus Production

Assignee: MICROBIX BIOSYSTEMS INCPriority: Jun 20, 2003Filed: Sep 17, 2007Published: Feb 5, 2009
Est. expiryJun 20, 2023(expired)· nominal 20-yr term from priority
C12N 7/00A61K 39/145C12N 2760/16034C12N 2760/16051A61K 39/12
49
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Claims

Abstract

An improved process for recovery of virus from allantoic fluid of virus-infected chick embryos. Virus associated with granular and fibrous debris in the allantoic fluid can be disassociated from the debris and recovered, thereby increasing viral yield. Dissociation can be achieved by subjecting the virus-debris complex to conditions of increased salt concentrations, e.g., 0.5 M or greater.

Claims

exact text as granted — not AI-modified
1 . A process for recovering virus from allantoic fluid of virus-infected chick embryos, comprising the steps of:
 (a) adding one or more salts to the allantoic fluid to generate a total salt concentration therein of about 0.5 M or greater; and   (b) recovering virus from the resulting fluid.   
   
   
       2 - 40 . (canceled)

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