Method of treating surface of substrate used in biological reaction system

Abstract

Provided is a method of treating a surface of a substrate used in a biochemical reaction system, the method including forming a polymer film on the surface by vapor deposition of a compound of formula (1) below and a compound of formula (2) below: (RO) 3 —Si—(CH 2 ) n1 —X  (1) (RO) 3 —Si—(CH 2 ) n2 —(CF 2 ) m —X  (2) wherein R is one of a methyl group and an ethyl group, X is one of a methyl group and a trifluoromethyl group, n1 is an integer from 1 to 3, n2 is an integer from 1 to 10, and m is an integer from 1 to 10.

1 . A biochemical reaction system, comprising:
 a substrate including a polymer film on a surface of the substrate, the polymer film being formed on the surface by vapor deposition of a compound of formula (1) below and a compound of formula (2) below:
   (RO) 3 —Si—(CH 2 ) n1 —X  (1) 
   (RO) 3 —Si—(CH 2 ) n2 —(CF 2 ) m —X  (2) 
   wherein R is one of a methyl group and an ethyl group, X is one of a methyl group and a trifluoromethyl group, n1 is an integer from 1 to 3, n2 is an integer from 1 to 10, and m is an integer from 1 to 10.   
   
   
       2 . The biochemical reaction system of  claim 1  being a polymerase chain reaction (PCR) system. 
   
   
       3 . The biochemical reaction system of  claim 1 , wherein the compound of said formula (1) and the compound of said formula (2) are simultaneously deposited by vaporization. 
   
   
       4 . The biochemical reaction system of  claim 1 , wherein the compound of said formula (1) and the compound of said formula (2) are sequentially deposited by vaporization. 
   
   
       6 . A composition for treating a surface of a substrate used in a biochemical reaction system, the composition comprising a compound of formula (1) below and a compound of formula (2) below:
   (RO) 3 —Si—(CH 2 ) n1 —X  (1)     (RO) 3 —Si—(CH 2 ) n2 —(CF 2 ) m —X  (2)   wherein R is one of a methyl group and an ethyl group, X is one of a methyl group and a trifluoromethyl group, n1 is an integer from 1 to 3, n2 is an integer from 1 to 10, and m is an integer from 1 to 10.