US2008312449A1PendingUtilityA1

New Compounds

Assignee: LINDBERG PER LENNARTPriority: May 28, 1993Filed: Feb 27, 2007Published: Dec 18, 2008
Est. expiryMay 28, 2013(expired)· nominal 20-yr term from priority
A61P 31/04A61P 29/00A61P 17/06A61P 1/00A61P 19/06A61P 1/04C07D 401/12A61K 31/44
61
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The novel optically pure compounds Na + , Mg 2+ , Li + , K + , Ca 2+ and N + (R) 4 salts of (+)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole or (−)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, in particular sodium and magnesium salt form thereof, where R is an alkyl with 1-4 carbon atoms, processes for the preparation thereof and pharmaceutical preparations containing the compounds as active ingredients, as well as the use of the compounds in pharmaceutical preparations and intermediates obtained by preparing the compounds.

Claims

exact text as granted — not AI-modified
1 - 34 . (canceled) 
   
   
       35 . An optically pure potassium salt of (−)-5-methoxy-2-[[(4-methoxy-3,5,dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole. 
   
   
       36 . The compound according to  claim 35 , wherein the compound is crystalline. 
   
   
       37 . Potassium salt of (−)-5-methoxy-2-[[(4-methoxy-3,5,dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole in an optical purity of at least about 94% enantiomeric excess. 
   
   
       38 . The compound according to  claim 37 , when the optical purity is at least 94% enantiomeric excess. 
   
   
       39 . The compound according to  claim 37 , wherein the compound is in crystalline form. 
   
   
       40 . The compound according to  claim 38 , wherein the compound is in crystalline form. 
   
   
       41 . Potassium salt of (−)-5-methoxy-2-[[(4-methoxy-3,5,dimethyl-2-pyridinyl)methyl]-sulfinyl]-1H-benzimidazole in an optical purity of at least about 99.8% enantiomeric excess. 
   
   
       42 . The compound according to  claim 41 , wherein the optical purity is at least 99.8% enantiomeric excess. 
   
   
       43 . The compound according to  claim 41 , wherein the compound is in crystalline form. 
   
   
       44 . The compound according to  claim 42 , wherein the compound is in crystalline form. 
   
   
       45 . A pharmaceutical formulation for administration comprising the potassium salt of any one of the preceding claims and a pharmaceutically acceptable carrier.

Join the waitlist — get patent alerts

Track US2008312449A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.