Herbal composition for treatment of neurodegeneration and neuronal dysfunction

Abstract

This invention provides methods of using various herbal compositions to treat neurodegenerative diseases and neuronal dysfunctions, said compositions comprise a combination of Radix angelica sinensis (DangGui), Ligusticum chuanxiong (ChuanXiong), Hirudo (ShuiZhi), Polygonatum sibiricum (HuangJing), Carthamus tinctorius (Hong Hua), Astragalus membranaceus (HuangQi), and Glycyrrhiza uralensis (Gancao).

1 - 12 . (canceled) 
   
   
       13 . A method of treating neurodegenerative diseases selected from the group consisting of motor neuron disease, cerebral palsy, Olivopontocerebellar atrophy, and ataxia, comprising the step of administering to a patient in need thereof a compositing consisting essentially of
 Radix angelica sinensis (DangGui) 0.82-3.3 g/kg body weight, Ligusticum chuanxiong (ChuanXiong) 0.1-1.2 g/kg body weight, Hirudo (ShuiZhi) 0.1-0.4 g/kg body weight, Polygonatum sibiricum (Huangjing) 0.2-0.8 g/kg body weight, Glycyrrhiza uralensis (Gancao) 0.06-0.21 g/kg body weight, Astragalus membranaceus (HuangQi) 0.315 g-1.2 g/Kg body weight, Curculigo orchioides (XianMao) 0.1-1 g/Kg body weight, epimedium grandiflorum (YinYangHuo) 0.1-1 g/Kg body weight, Psoralea corylifolia (BuGuZhi) 0.1-1 g/Kg body weight, Leonurus heterophyllus (YiMuCao) 0.1-1 g/Kg body weight, and Paeonia rubrae (ChiShao) 0.1-1 g/Kg body weight,   wherein the g/kg body weight dosages can be increased up to 2.5 times if the body weight of the patient is less than 40 kg.   
   
   
       14 . The method of  claim 13 , wherein Ligusticum chuanxiong (ChuanXiong) is replaced by Carthamus tinctorius (Hong Hua) 0.1-1.2 g/kg body weight. 
   
   
       15 . The method of  claim 13 , wherein the composition is administered daily. 
   
   
       16 . A method of treating neurodegenerative diseases selected from the group consisting of motor neuron disease, cerebral palsy, Olivopontocerebellar atrophy, and ataxia, comprising the step of administering to a patient in need thereof a compositing consisting essentially of
 Radix angelica sinensis (DangGui) 0.82-3.3 g/kg body weight, Ligusticum chuanxiong (ChuanXiong) 0.1-1.2 g/kg body weight, Hirudo (ShuiZhi) 0.1-0.4 g/kg body weight, Polygonatum sibiricum (Huangjing) 0.2-0.8 g/kg body weight, Glycyrrhiza uralensis (Gancao) 0.06-0.21 g/kg body weight, Astragalus membranaceus (HuangQi) 0.315 g-1.2 g/Kg body weight, Lycium chinensis mill (GouQiZi) 0.1-1 g/Kg body weight, Curculigo orchioides (XianMao) 0.1-1 g/Kg body weight, epimedium grandiflorum (YinYangHuo) 0.1-1 g/Kg body weight, Cornus officinalis (ShanZhuYu) 0.1-1 g/Kg body weight, Psoralea corylifolia (BuGuZhi) 0.1-1 g/Kg body weight, Leonurus heterophyllus (YiMuCao) 0.1-1 g/Kg body weight, and Paeonia rubrae (ChiShao) 0.1-1 g/Kg body weight,   wherein the g/kg body weight dosages can be increased up to 2.5 times if the body weight of the patient is less than 40 kg.   
   
   
       17 . The method of  claim 16 , wherein Ligusticum chuanxiong (ChuanXiong) is replaced by Carthamus tinctorius (Hong Hua) 0.1-1.2 g/kg body weight. 
   
   
       18 . The method of  claim 16 , wherein the composition is administered daily. 
   
   
       19 . A method of treating neurodegenerative diseases selected from the group consisting of motor neuron disease, cerebral palsy, Olivopontocerebellar atrophy, and ataxia, comprising the step of administering to a patient in need thereof a compositing consisting essentially of
 Radix angelica sinensis (DangGui) 0.82-3.3 g/kg body weight, Ligusticum chuanxiong (ChuanXiong) 0.1-1.2 g/kg body weight, Hirudo (ShuiZhi) 0.1-0.4 g/kg body weight, Polygonatum sibiricum (HuangJing) 0.2-0.8 g/kg body weight, Glycyrrhiza uralensis (Gancao) 0.06-0.21 g/kg body weight, Astragalus membranaceus (HuangQi) 0.315 g-1.2 g/Kg body weight, Lycium chinensis mill (GouQiZi) 0.1-1 g/Kg body weight, Curculigo orchioides (XianMao) 0.1-1 g/Kg body weight, epimedium grandiflorum (YinYangHuo) 0.1-1 g/Kg body weight, Cornus officinalis (ShanZhuYu) 0.1-1 g/Kg body weight, Psoralea corylifolia (BuGuZhi) 0.1-1 g/Kg body weight, Leonurus heterophyllus (YiMuCao).0.1-1 g/Kg body weight, and Paeonia rubrae (ChiShao) 0.1-1 g/Kg body weight, Plastrum testudinis (GuiBan) 0.1-1 g/Kg body weight.   wherein the g/kg body weight dosages can be increased up to 2.5 times if the body weight of the patient is less than 40 kg.   
   
   
       20 . The method of  claim 19 , wherein Ligusticum chuanxiong (ChuanXiong) is replaced by Carthamus tinctorius (Hong Hua) 0.1-1.2 g/kg body weight. 
   
   
       21 . The method of  claim 19 , wherein the composition is administered daily.