Meloxicam for the treatment of respiratory diseases in pigs

Abstract

A method of treating or preventing a respiratory disease in a pig, the method comprising administering to the pig in need thereof an effective amount of meloxicam or a pharmaceutically acceptable salt thereof.

1 . A method of treating or preventing a respiratory disease in a pig, the method comprising administering to the pig in need thereof an effective amount of the pharmaceutical composition of  claim 23 . 
     
     
         2 . The method according to  claim 1 , wherein said pharmaceutical composition is administered systemically or orally. 
     
     
         3 . The method according to  claim 1 , wherein said pharmaceutical composition is administered in a daily dose ranging from 0.01 mg/kg to 5.0 mg/kg. 
     
     
         4 . The method according to  claim 2 , wherein said pharmaceutical composition is administered in a daily dose ranging from 0.01 mg/kg to 5.0 mg/kg. 
     
     
         5 . The method according to  claim 1 , wherein said pharmaceutical composition is administered by injection. 
     
     
         6 . The method according to  claim 2 , wherein said pharmaceutical composition is administered by injection. 
     
     
         7 . The method according to  claim 1 , wherein said pharmaceutical composition is administered via drinking water or as top dressing on feed in soluble granules. 
     
     
         8 . The method according to  claim 2 , wherein said pharmaceutical composition is administered via drinking water or as top dressing on feed in soluble granules. 
     
     
         9 - 10 . (canceled) 
     
     
         11 . The method according to  claim 1 , wherein the antibiotic in the pharmaceutical composition of  claim 23  is selected from the group consisting of β-lactams, quinolones, tetracyclines, sulfonamides, fenicoles, and macrolides. 
     
     
         12 . The method according to  claim 2 , wherein the antibiotic in said pharmaceutical composition of  claim 23  is selected from the group consisting of β-lactams, quinolones, tetracyclines, sulfonamides, fenicoles, and macrolides. 
     
     
         13 . The method according to  claim 1 , wherein the antibiotic in said pharmaceutical composition of  claim 23  is oxytetracycline or chlorotetracycline. 
     
     
         14 . The method according to  claim 2 , wherein the antibiotic in said pharmaceutical composition of  claim 23  is oxytetracycline or chlorotetracycline. 
     
     
         15 . The method according to  claim 1 , wherein the disease is Porcine Respiratory Disease Complex and the pig is a growing or fattening pig. 
     
     
         16 . The method according to  claim 2 , wherein the disease is Porcine Respiratory Disease Complex and the pig is a growing or fattening pig. 
     
     
         17 . The method according to  claim 1 , wherein the disease is caused by mycoplasmas, bacteria, or viruses. 
     
     
         18 . The method according to  claim 2 , wherein the disease is caused by mycoplasmas, bacteria, or viruses. 
     
     
         19 . The method according to  claim 1 , wherein the disease is caused by  Mycoplasma hyopneumoniae, Mycoplasma hyorhinis, Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, Pasteurella multocida, Arcanobacterium pyogenes , Swine Influenza Virus, Aujetzky's Virus, Porcine Reproductive and Respiratory Syndrome Virus, Porcine Circovirus, and Transmissible Gastroenteritis and Porcine Respiratory Coronavirus. 
     
     
         20 . The method according to  claim 2 , wherein the disease is caused by  Mycoplasma hyopneumoniae, Mycoplasma hyorhinis, Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, Pasteurella multocida, Arcanobacterium pyogenes , Swine Influenza Virus, Aujetzky's Virus, Porcine Reproductive and Respiratory Syndrome Virus, Porcine Circovirus, and Transmissible Gastroenteritis and Porcine Respiratory Coronavirus. 
     
     
         21 . The method according to  claim 1 , wherein the disease is caused by  Actinobacillus  spp.,  Streptococcus  spp., or  Staphylococcus  spp. 
     
     
         22 . The method according to  claim 2 , wherein the disease is caused by  Actinobacillus  spp.,  Streptococcus  spp., or  Staphylococcus  spp. 
     
     
         23 . A ready-to-use two-component pharmaceutical composition for the treatment of respiratory diseases in pigs, the composition comprising:
 (a) a first component comprising meloxicam or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier; and   (b) a second component comprising one or more antibiotics selected from the group consisting of β-lactams, quinolones, tetracyclines, sulfonamides, fenicoles, and macrolides, and a pharmaceutically acceptable carrier.