Method of Manufacturing Packaging Comprising Pharmaceutical Products

Abstract

The method for producing a multi-day package containing various drugs has the following steps: a bottom layer is formed with a plurality of wells arranged in a pattern; a predetermined number of different drugs is arranged in predetermined positions at various dispensing stations of a filling device; the desired number of drugs are picked in a controlled manner from their predetermined positions at each dispensing station by at least one movable suction or gripper device, and the drugs are deposited in the predetermined wells; and a sealing film is applied to the bottom layer to seal off the wells. In the course of this method, in at least one dispensing station several suction or gripper devices, which are arranged in correspondence with the pattern of the wells in the multi-day package and which travel parallel to each other, are actuated individually.

1 . A method for producing a multi-day package containing various drugs comprising the following steps:
 forming a bottom layer with a plurality of wells arranged in a pattern;   arranging a predetermined number of different drugs in predetermined positions at various dispensing stations of a filling device;   picking the desired number of drugs in a controlled manner from their predetermined positions at each dispensing station by at least one movable suction or gripper device, and placing the drugs in predetermined wells; and   applying a sealing film to the bottom layer to seal off the wells,   
     wherein, in at least one dispensing station, several suction or gripper devices are arranged in correspondence with the pattern of the wells in the multi-day package, are actuated individually and travel parallel to each other. 
   
   
       2 . The method of  claim 1  wherein the step of arranging a predetermined number of a drug in predetermined positions at a dispensing station of a filling device includes the following steps:
 forming a base layer extending a considerable distance in the longitudinal and transverse directions, as a result of which the plurality of supply-blister pockets is obtained; and   loading the drugs into the supply-blister pockets;   sealing the supply-blister pockets with a temporary sealing film, which is applied adhesively to the webs of the base layer between the supply-blister pockets, as a result of which a supply-blister sheet is formed; and   partially removing the temporary sealing film from the supply-blister sheet to release a predetermined number of drugs to the suction or gripper devices.   
   
   
       3 . The method of  claim 2  further comprising the additional step that, before the step of removing the temporary sealing film from the supply-blister sheet, the supply-blister sheet is cut into supply-blister sections, and the supply-blister sections are arranged on rolls at the dispensing station transversely to the transport direction of the multi-day package. 
   
   
       4 . The method of  claim 1  wherein the step of arranging a predetermined number of a drug in predetermined positions at a dispensing station of a filling device comprises the step of filling the holders of a sorting plate with drugs, the holders being arranged in correspondence with the pattern of the multi-day package. 
   
   
       5 . The method of  claim 4  wherein the sorting plate is filled completely by an oscillating movement of a vibrating chute, followed by a brushing movement of a brush device. 
   
   
       6 . The method of  claim 1  wherein each of the minimum of one suction or gripper devices is monitored by means of a camera or by sensors. 
   
   
       7 . The method of  claim 1  further comprising the additional steps that perforations are introduced into the bottom layer and into the sealing film between the wells.