4''-Substituted Erythromycin Derivative

Abstract

A compound of formula (I) and/or pharmaceutically acceptable derivatives thereof, having antimicrobial activity, processes for their preparation, compositions containing them and to their use in medicine.

1 . A compound of formula (I) 
       
         
           
           
               
               
           
         
         or a pharmaceutically acceptable derivative thereof. 
       
     
     
         2 . The compound 4″-O-{2-[(3-[3-Carboxy-1-dimethylamino-4-oxo-1,4-dihydro-6-quinolinyl]propyl)methylamino]ethyl}-6-O-methyl-erythromycin A. 
     
     
         3 - 6 . (canceled) 
     
     
         7 . A method for the treatment of the human or non-human animal body to combat microbial infection comprising administration to a body in need of such treatment of an effective amount of a compound as claimed in  claim 1 , or a pharmaceutically acceptable derivative thereof. 
     
     
         8 . A pharmaceutical composition comprising a compound as claimed in  claim 1 , or a pharmaceutically acceptable derivative thereof, in association with a pharmaceutically acceptable excipient, diluent and/or carrier. 
     
     
         9 . A method for the treatment of the human or non-human animal body to combat microbial infection comprising administration to a body in need of such treatment of an effective amount of a compound as claimed in  claim 2 . 
     
     
         10 . A pharmaceutical composition comprising a compound as claimed in  claim 2  in association with a pharmaceutically acceptable excipient, diluent and/or carrier.