Systems and methods for the accurate delivery of flow materials

Abstract

Pumps and flow regulators provide relatively constant and known flow volume over time while maintaining isolation of the flow material. The pumps of the present disclosure provide real time monitoring of the volume of flow material delivered over time, and provides for adjustment of the pump or flow regulators to modulate the flow rate. Thus, flow may be substantially modeled to a desired flow profile with real time adjustments of the flow rates.

1 . A system comprising:
 an pump that is configured to measure flow rate of a flow material in about real time; and   at least one flow regulator for providing substantially constant flow rate;   wherein at least one operating parameter of the pump is adjustable to change the flow rate in about real time.   
   
   
       2 . The system of  claim 1 , wherein the at least one flow regulator comprises a variable flow reshapable flow restrictor. 
   
   
       3 . The system of  claim 1 , wherein the at least one flow regulator comprises an adjustable clamp system. 
   
   
       4 . The system of  claim 1 , wherein the at least one flow regulator comprises a variable flow reshapable flow restrictor and an adjustable clamp system. 
   
   
       5 . The system of  claim 1 , wherein the flow material is isolated from the devices of the pump for pumping the flow material and measuring the flow material. 
   
   
       6 . The system of  claim 1 , wherein the flow material is contained in a sterile chamber and the pump preserves the sterility of the flow material. 
   
   
       7 . The system of  claim 1 , wherein the pump comprises at least two chambers. 
   
   
       8 . The system of  claim 7 , wherein the pump comprises at least three chambers. 
   
   
       9 . The system of  claim 7 , wherein the pump comprises at least three chambers. 
   
   
       10 . The system of  claim 1 , further comprising a microprocessing unit that is configured to accept and substantially execute a flow profile. 
   
   
       11 . A method comprising providing:
 a pump capable of measuring flow rate of a flow material in about real time;   a microprocessor for determining a flow volume over an elapsed time period; and   a flow regulator for modulating a flow rate within a specified range of flow rates;   wherein the flow material is isolated from the devices used to measure flow rate.   
   
   
       12 . The method of  claim 11 , wherein the at least one flow regulator comprises a variable flow reshapable flow restrictor. 
   
   
       13 . The method of  claim 11 , wherein the at least one flow regulator comprises an adjustable clamp system. 
   
   
       14 . The method of  claim 11 , wherein the at least one flow regulator comprises a variable flow reshapable flow restrictor and an adjustable clamp system. 
   
   
       15 . The method of  claim 11 , wherein the flow material is isolated from the devices of the pump for pumping the flow material and measuring the flow material. 
   
   
       16 . The method of  claim 11 , wherein the flow material is contained in a sterile chamber and the pump preserves the sterility of the flow material. 
   
   
       17 . The method of  claim 11 , wherein the pump comprises at least two chambers. 
   
   
       18 . The method of  claim 17 , wherein the pump comprises at least three chambers. 
   
   
       19 . The method of  claim 17 , wherein the pump comprises at least three chambers. 
   
   
       20 . The method of  claim 11 , further comprising a microprocessing unit that is configured to accept and substantially execute a flow profile.